MF Researcher Database

Researchers Database

Advance

IMAEDA Kenro

    Graduate School of Medical Sciences Department of Gastroenterology and Metabolism
Contact： kimaedamed.nagoya-cu.ac.jp
Last Updated :2024/03/19

Researcher Information

J-Global ID

Research Interests

  • インスリン抗体   消化管運動   平滑筋   糖尿病   

Research Areas

  • Life sciences / Metabolism and endocrinology

Association Memberships

  • Japan Society of Smooth Muscle Research   日本消化器内視鏡学会   日本消化器病学会   Japanese Sciety of Internal Medicine   Japan Diabetes Sciety   

Published Papers

Books etc

  • Membrane potential and calcium responses evoked by acetylcholine in submucosal arterioles of the guinea-pig small intestine
    2002

MISC

Awards & Honors

  • 1998 上原生命科学記念財団ポストドクタルフェローシップ
  • 1997 大幸財団学術奨励賞

Research Grants & Projects

  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research
    Date (from‐to) : 2014/04 -2017/03 
    Author : Kikuchi Chigusa
     
    In this study, we examined vascular endothelium function using diabetes model animals and questionnaire on factors of going for a medical checkup for women to clarify the mechanism of vascular endothelium dysfunction mediated by sex difference. In diabetes model female rats, post-occlusive hind limb reactive hyperemia index was decreased as compared with control rats at early stage. As the result of the questionnaire, many women were under stress. It was suggested that especially child rearing and economic factors prevent women from going for a medical checkup.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research
    Date (from‐to) : 2011 -2013 
    Author : KIKUCHI CHIGUSA; MATSUNAGA Tamihide; IMAEDA Kenro; SUZUKI Tadashi; KAJIKURI Jyunko
     
    In this study, we examined the mechanism of vascular dysfunction mediated by postprandial hyperglycemia and the effects of new antidiabetes agent, dipeptidyl peptidase 4 (DPP-4) inhibitor using model animals and patient's data. Onset of atherosclerotic disease in diabetic patients was depend on circadian rhythm of blood glucose. Protein kinase C delta was decreased and reactive oxygen species via eNOS uncoupling was increased in the vascular wall of postprandial hyperglycemia model animals. Chronic administration of DPP-4 inhibitor suppresses postprandial hyperglycemia and decreased reactive oxygen species production.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research
    Date (from‐to) : 2011 -2012 
    Author : TAKAISHI Tetsuo; WATANABE Miyuki; IMAEDA Kenro
     
    People with diabetes mellitus or impaired glucose tolerance need to reduce blood glucose level immediately after eating. A walking for about 1 hour after eating is effective to reduce blood glucose level. However, it is difficult for most of full time workers to have time for such a walking every day. This study clarified that a short bout of stair climbing-descending exercise with a flight of stairs with about 20 steps effectively reduce blood glucose level without a feeling of fatigue. In addition, this study suggested that an exercise intervention for a certain period of time with the stair climbing-descending exercise leads to an improvement of glucose torelance.

Other link

researchmap


Copyright © MEDIA FUSION Co.,Ltd. All rights reserved.