Researcher Database



FacultyGraduate School of Pharmaceutical Sciences Department of Biomedical Science
Last Updated :2020/01/09

Researcher Profile and Settings


  • Ph.D, University of Tokyo

Research Activities

Research Areas

  • Biological science, Molecular biology
  • Neuroscience, Neurochemistry/Neuropharmacology

Published Papers

  • Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathway., Nishino K, Watanabe S, Shijie J, Murata Y, Oiwa K, Komine O, Endo F, Tsuiji H, Abe M, Sakimura K, Mishra A, Yamanaka K., Acta Neuropathol Commun., 7, (1) , 07 , Refereed
  • Reducing ADAMTS-3 Inhibits Amyloid ╬▓ Deposition in App Knock-in Mouse., Yamakage Y, Tsuiji H, Kohno T, Ogino H, Saito T, Saido TC, Hattori M, Biological & pharmaceutical bulletin, 42, (3) 354 - 356, Refereed
  • Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin., Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, The Journal of neuroscience : the official journal of the Society for Neuroscience, 37, (12) 3181 - 3191, 03 , Refereed
  • Reelin deficiency leads to aberrant lipid composition in mouse brain., Mizukami T, Ikeda K, Shimanaka Y, Korogi K, Zhou C, Takase H, Tsuiji H, Kono N, Kohno T, Arai H, Arita M, Hattori M, Biochemical and biophysical research communications, 505, (1) 81 - 86, 10 , Refereed
  • TDP-43 accelerates age-dependent degeneration of interneurons., Tsuiji H*, Inoue I, Takeuchi M, Furuya A, Yamakage Y, Watanabe S, Koike M, Hattori M, Yamanaka K*, Scientific reports, 7, (1) , 11 , Refereed, *: corresponding author
  • There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS., Gitler AD*, Tsuiji H*, Brain research, 1647, 19 - 29, 09 , Refereed, *: corresponding author
  • Establishment of In┬áVitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells., Ichiyanagi N, Fujimori K, Yano M, Ishihara-Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuiji H, Suzuki N, Warita H, Aoki M, Okano H, Stem cell reports, 6, (4) 496 - 510, 03 , Refereed
  • Spliceosome integrity is defective in the motor neuron diseases ALS and SMA., Tsuiji H*, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H, Murayama S, Sobue G, Yamanaka K*, EMBO molecular medicine, 5, (2) 221 - 234, 02 , Refereed, *: corresponding author
  • Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1., Tsuiji H, Yoshimoto R, Hasegawa Y, Furuno M, Yoshida M, Nakagawa S, Genes to cells : devoted to molecular & cellular mechanisms, 16, (5) 479 - 490, 05 , Refereed
  • Cadherin conformations associated with dimerization and adhesion., Tsuiji H, Xu L, Schwartz K, Gumbiner BM, The Journal of biological chemistry, 282, (17) 12871 - 12882, 04 , Refereed
  • Aberrant O-glycosylation inhibits stable expression of dysadherin, a carcinoma-associated antigen, and facilitates cell-cell adhesion., Tsuiji H, Takasaki S, Sakamoto M, Irimura T, Hirohashi S, Glycobiology, 13, (7) 521 - 527, 07 , Refereed
  • Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations., Yamamoto Y, Sakamoto M, Fujii G, Tsuiji H, Kenetaka K, Asaka M, Hirohashi S, Hepatology (Baltimore, Md.), 37, (3) 528 - 533, 03 , Refereed
  • Malignant and other properties of human colon carcinoma cells after suppression of sulfomucin production in vitro., Tsuiji H, Nakatsugawa S, Ishigaki T, Irimura T, Clinical & experimental metastasis, 17, (2) 97 - 104, 03 , Refereed
  • Expression of mucin-associated sulfo-Lea carbohydrate epitopes on human colon carcinoma cells., Tsuiji H, Hayashi M, Wynn DM, Irimura T, Japanese journal of cancer research : Gann, 89, (12) 1267 - 1275, 12 , Refereed
  • Novel carbohydrate specificity of monoclonal antibody 91.9H prepared against human colonic sulfomucin: recognition of sulfo-Lewis(a) structure., Tsuiji H, Hong JC, Kim YS, Ikehara Y, Narimatsu H, Irimura T, Biochemical and biophysical research communications, 253, (2) 374 - 381, 12 , Refereed
  • Monoclonal antibody 91.9H raised against sulfated mucins is specific for the 3'-sulfated Lewisa tetrasaccharide sequence., Loveless RW, Yuen CT, Tsuiji H, Irimura T, Feizi T, Glycobiology, 8, (12) 1237 - 1242, 12 , Refereed
  • Expression of mucin genes and carbohydrate epitopes in 19 human colon carcinoma cell lines., Iida S, Tsuiji H, Nemoto Y, Sano Y, Reddish MA, Irimura T, Oncology research, 10, (8) 407 - 414, Refereed

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