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SHIMOHIRA Masashi

    Graduate School of Medical Sciences Department of Radiology　Associate Professor
Contact： mshimohiragmail.com
Last Updated :2024/04/24

Researcher Information

Research funding number

  • 60597821

J-Global ID

Research Interests

  • 放射線医学   IVR   

Research Areas

  • Life sciences / Radiology

Academic & Professional Experience

  • 2019/04 - Today  Nagoya City UniversityGraduate School of Medical Sciences, Department of Radiology准教授
  • 2015/04 - 2019/03  Nagoya City UniversityGraduate School of Medical Sciences, Department of Radiology講師
  • 2011/04 - 2015/03  Nagoya City UniversityGraduate School of Medical Sciences, Department of Radiology助教
  • 2010/04 - 2011/03  Nagoya City UniversityGraduate School of Medical Sciences, Department of Radiology臨床研究医
  • 2009/04 - 2010/03  米国オレゴン健康科学大学放射線科研究員
  • 2007/07 - 2009/03  Nagoya City UniversityGraduate School of Medical Sciences, Department of Radiology臨床研究医
  • 2006/04 - 2007/06  成田記念病院放射線科医員
  • 2005/04 - 2006/03  Nagoya City UniversityGraduate School of Medical Sciences, Department of Radiology臨床研究医
  • 2003/04 - 2005/03  Nagoya City UniversityGraduate School of Medical Sciences, Department of Radiology臨床研修医
  • Research Fellow of Dotter Interventional Institute (2009.4-2010.3)

Education

  •        - 2011/03  Nagoya City University
  •        - 2003/03  Nagoya City University  医学部

Association Memberships

  • The Japanese Society of Interventional Radiology   Japan Radiological Society   日本HHT研究会   日本末梢血管塞栓療法研究会   日本救急放射線研究会   THE JAPANESE ASSOCIATION FOR THE SURGERY OF TRAUMA   JAPANESE ASSOCIATION FOR ACUTE MEDICINE   JAPANESE SOCIETY OF NUCLEAR MEDICINE   

Published Papers

MISC

Awards & Honors

  • 2016/04 アジア太平洋IVR学会 優秀演題賞
     
    受賞者: 下平 政史
  • 2014/06 日本IVR学会 優秀演題賞
     
    受賞者: 下平 政史

Research Grants & Projects

  • 日本学術振興会：科学研究費助成事業
    Date (from‐to) : 2023/04 -2026/03 
    Author : 橋爪 卓也; 杉浦 真由美; 樋渡 昭雄; 下平 政史
  • 日本学術振興会：科学研究費助成事業 基盤研究(C)
    Date (from‐to) : 2023/04 -2026/03 
    Author : 下平 政史
  • 日本学術振興会：科学研究費助成事業 基盤研究(C)
    Date (from‐to) : 2021/04 -2024/03 
    Author : 中川 基生; 齋藤 伸治; 野澤 久美子; 下平 政史; 小澤 良之
     
    当院において3DT1強調像が撮像された小児頭部MRI800例、神奈川県立こども医療センターで3DT1強調像が撮像された小児頭部MRI60例の画像データを収集した。これらの症例の臨床データ、遺伝学的検査結果を収集した。画像データから矢状断像、顔貌の3D画像データを抽出し、AIによる診断ソフトを、Sony社製Neural Network Console、MathWorks社製MATLABを用いて作成中である。 本研究による成果は、第82回日本医学放射線学会(横浜)、Radiological Society of North America Annual Meeting 2022で発表予定である。
  • 日本学術振興会：科学研究費助成事業 基盤研究(C)
    Date (from‐to) : 2020/04 -2023/03 
    Author : 下平 政史; 中川 基生; 富田 夏夫; 荒井 信行; 河合 辰哉; 菅 博人; 小澤 良之
     
    これまで集積した患者データ、画像を検討、解析した。結果は下記の通りである。19患者(男性４名、女性15名、年齢中央値46歳（20ー73歳）)の21病変の肺動静脈奇形に対しコイル塞栓術が施行された。 その術前に造影time-resolved magnetic resonance angiography（TR-MRA）および非造影MRAが撮影された。非造影MRAの有用性を造影TR-MRAと比較し、病変描出能、画質を検討した。画質については5-point Likert scale （1 = poor, 2 = fair, 3 = moderate, 4 = good, 5 = excellent）を使用した。 肺動静脈奇形のfeederのサイズは、中央値3.5mm（2.3―5.7）。Sacのサイズは、中央値7.8mm（4.1―12.5）であった。病変描出能は非造影MRA、造影TR-MRAともに100％であった。画質の評価スコアは、非造影MRA(3.2 ± 1.2)は造影TR-MRA (4.9 ± 0.3)よりも有意に低かった(P<0.0001)。 今回の研究の初期経験は、第8回日本HHT研究会および16th Annual Scientific Meeting of Asia Pacific Society of Cardiovascular and Interventional Radiologyで発表した。さらにMagnetic Resonance Imagingに投稿し、掲載された。
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research
    Date (from‐to) : 2018/04 -2021/03 
    Author : Nakagawa Motoo
     
    Dual energy CT was performed on patients with bladder cancer, and monoenergetic images equivalent to 40 keV were reconstructed from the data of the images. These image data were compared with the image data of normal tube voltage 120 kVp imaging to examine whether there is a difference in the detection ability of bladder cancer. A comparison of the contrast effect of bladder cancer showed that the 40 keV images showed stronger contrast than the conventional 120 kVp images (P<0.01). The 40 keV images were also significantly more sensitive in detecting bladder cancer in subjective diagnostic imaging. These results were published in an English journal (Jpn J Radiol. 2022;40:177-183).
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 2018/04 -2021/03 
    Author : Hiroshi Kondo
     
    Twenty-five IR physicians nationwide who performed IR wearing radiation protective eyeglasses during the one-year. Personal dosimeters were attached to the outer and inner surfaces of the left lens of the protective glasses and were collected every month to measure the 3-mm dose equivalent (Do) of the outer surface of the lens and the 3-mm dose equivalent (Di) of the inner surface of the lens. The correlations with the 70 μm dose equivalent (Dn) estimated from personal dosimeters distributed separately and worn on the neck were also confirmed. The mean monthly values of Do, Di, and Dn were 0.89, 0.40, and 1.18 mSV, respectively. Do showed a strong correlation with Dn and Di, respectively. 3 doctors (12%) exceeded 20 mSv/year, although there were no doctors whose Do exceeded 50 mSV/year. The IR physicians ’s dose to the eye lens can exceed the equivalent dose limit, particularly when radiation protection glasses, which decrease the exposure dose by about 50%, are not used.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research
    Date (from‐to) : 2018/04 -2021/03 
    Author : Ozawa Yoshiyuki
     
    It is often difficult to diagnose the mediastinal tumors on CT because of their similar imaging findings. We evaluated the utility of the texture analysis for improving diagnostic accuracy of the mediastinal tumors on CT. NGLDM Contrast, GLCM Correlation, GLZLM SZLGE, DISCRETIZED HISTOEntropy log2, DISCRETIZED HUmin were selected for differentiating thymic cysts from thymic epithelial tumors. Sphericity was selected for differentiating low-risk group from high-risk group + thymic carcinoma.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 2016/04 -2019/03 
    Author : YAMAKADO Koichiro
     
    A prospective multi-center clinical trial was performed to evaluate the clinical utility of hepatic arterial embolization using microsphere in patients with treatment refractory liver metastases. The primary endpoint was response rate at 1 month after embolization, and secondary ones were over all and progression-free survival, and safety. Microsphere was injected slowly from the hepatic artery until hepatic arterial blood flow stagnated. The response rate was as high as 50% at 1 month after embolization with a median survival of 9 months and progression survival of 4 months. There was no severe (G3 or 4) adverse events but increase in liver enzyme. Embolization using microsphere is a safe and useful treatment for patients with treatment refractory liver metastases.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 2016/04 -2019/03 
    Author : ISHIKURA Reiichi
     
    This prospective study was conducted to evaluate clinical utility of transarterial chemoembolization (TACE) using drug-eluting beads (DEB) in patients with hepatocellular carcinoma (HCC) refractory to conventional TACE using lipiodol (Lip-TACE). The primary endpoint was response rate at 1 month after DEB-TACE and the secondary ones were adverse events, and progression-free and overall survival. Patient entry (24 patients) have been completed and patients are being followed up. At the end of 2019, The follow-up will end and primary and secondary endpoints will be evaluated.
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
    Date (from‐to) : 2015/04 -2019/03 
    Author : Shimohira Masashi
     
    Pulmonary arteriovenous malformations (PAVMs) are abnormal fistulas that appear between the pulmonary arteries and veins that bypass the normal capillaries. Coil embolization is widely performed for PAVMs; however, recanalization of PAVM can be a problem after embolization. To prevent recanalization, the feeding artery of a PAVM should be embolized tightly. The purpose of this study was to evaluate the usefulness of hydrogel-coated coils in preventing recanalization after coil embolization of PAVMs. Thirty-seven consecutive patients with 57 untreated PAVMs underwent coil embolization with hydrogel-coated coils. In 56 of 57 PAVMs, embolization was successfully performed with hydrogel-coated coils. There was no recanalization with a mean follow-up period of 19 months in 56 PAVMs embolized with hydrogelcoated coils. There were no major complications. Hydrogel-coated coils may be useful for preventing recanalization after the embolization of PAVMs.

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