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五十川 正記イソガワ マサノリ

所属部署医学研究科ウイルス学分野
職名講師
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Last Updated :2019/07/06

研究活動情報

論文

  • Type I interferon signaling prevents hepatitis B virus-specific T cell responses by reducing antigen expression., Kawashima K, Isogawa M, Hamada-Tsutsumi S, Baudi I, Saito S, Nakajima A, Tanaka Y, Journal of virology,   2018年09月, 査読有り
  • Intrahepatic Cross-Presentation and Hepatocellular Antigen Presentation Play Distinct Roles in the Induction of HBV-Specific CD8+ T Cell Responses., Murata Y, Kawashima K, Sheikh K, Tanaka Y, Isogawa M, Journal of virology,   2018年08月, 査読有り
  • A novel association between core mutations in hepatitis B virus genotype F1b and hepatocellular carcinoma in Alaskan Native People., Hayashi S, Khan A, Simons BC, Homan C, Matsui T, Ogawa K, Kawashima K, Murakami S, Takahashi S, Isogawa M, Ikeo K, Mizokami M, McMahon BJ, Tanaka Y, Hepatology (Baltimore, Md.),   2018年06月, 査読有り
  • Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection., Matsuura K, Sawai H, Ikeo K, Ogawa S, Iio E, Isogawa M, Shimada N, Komori A, Toyoda H, Kumada T, Namisaki T, Yoshiji H, Sakamoto N, Nakagawa M, Asahina Y, Kurosaki M, Izumi N, Enomoto N, Kusakabe A, Kajiwara E, Itoh Y, Ide T, Tamori A, Matsubara M, Kawada N, Shirabe K, Tomita E, Honda M, Kaneko S, Nishina S, Suetsugu A, Hiasa Y, Watanabe H, Genda T, Sakaida I, Nishiguchi S, Takaguchi K, Tanaka E, Sugihara J, Shimada M, Kondo Y, Kawai Y, Kojima K, Nagasaki M, Tokunaga K, Tanaka Y, Japanese Genome-Wide Association Study Group for Viral Hepatitis., Gastroenterology, 152, (6) 1383 - 1394,   2017年05月, 査読有り
  • A new class of hepatitis B and D virus entry inhibitors, proanthocyanidin and its analogs, that directly act on the viral large surface proteins., Tsukuda S, Watashi K, Hojima T, Isogawa M, Iwamoto M, Omagari K, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Sureau C, Wakita T, Hepatology (Baltimore, Md.), 65, (4) 1104 - 1116,   2017年04月, 査読有り
  • Characteristics of escape mutations from occult hepatitis B virus infected patients with hematological malignancies in South Egypt., Elkady A, Iijima S, Aboulfotuh S, Mostafa Ali E, Sayed D, Abdel-Aziz NM, Ali AM, Murakami S, Isogawa M, Tanaka Y, World journal of hepatology, 9, (9) 477 - 486,   2017年03月, 査読有り
  • Molecular epidemiology of co-infection with hepatitis B virus and human immunodeficiency virus (HIV) among adult patients in Harare, Zimbabwe., Baudi I, Iijima S, Chin'ombe N, Mtapuri-Zinyowera S, Murakami S, Isogawa M, Hachiya A, Iwatani Y, Tanaka Y, Journal of medical virology, 89, (2) 257 - 266,   2017年02月, 査読有り
  • Host genetic variants influencing the clinical course of hepatitis B virus infection., Matsuura K, Isogawa M, Tanaka Y, Journal of medical virology, 88, (3) 371 - 379,   2016年03月, 査読有り
  • [Immune responses to HBV infection]., Isogawa M, Tanaka Y, Nihon rinsho. Japanese journal of clinical medicine, 73 Suppl 9, 397 - 401,   2015年12月, 査読有り
  • Host-virus interactions in hepatitis B virus infection., Guidotti LG, Isogawa M, Chisari FV, Current opinion in immunology, 36, 61 - 66,   2015年10月, 査読有り
  • Characterization of novel entecavir resistance mutations., Hayashi S, Murakami S, Omagari K, Matsui T, Iio E, Isogawa M, Watanabe T, Karino Y, Tanaka Y, Journal of hepatology, 63, (3) 546 - 553,   2015年09月, 査読有り
  • Immunosurveillance of the liver by intravascular effector CD8(+) T cells., Guidotti LG, Inverso D, Sironi L, Di Lucia P, Fioravanti J, Ganzer L, Fiocchi A, Vacca M, Aiolfi R, Sammicheli S, Mainetti M, Cataudella T, Raimondi A, Gonzalez-Aseguinolaza G, Protzer U, Ruggeri ZM, Chisari FV, Isogawa M, Sitia G, Iannacone M, Cell, 161, (3) 486 - 500,   2015年04月, 査読有り
  • Immunobiology of hepatitis B virus infection., Isogawa M, Tanaka Y, Hepatology research : the official journal of the Japan Society of Hepatology, 45, (2) 179 - 189,   2015年01月, 査読有り
  • Validation of cross-genotype neutralization by hepatitis B virus-specific monoclonal antibodies by in vitro and in vivo infection., Hamada-Tsutsumi S, Iio E, Watanabe T, Murakami S, Isogawa M, Iijima S, Inoue T, Matsunami K, Tajiri K, Ozawa T, Kishi H, Muraguchi A, Joh T, Tanaka Y, PloS one, 10, (2) ,   2015年, 査読有り
  • CD40 activation rescues antiviral CD8⁺ T cells from PD-1-mediated exhaustion., Isogawa M, Chung J, Murata Y, Kakimi K, Chisari FV, PLoS pathogens, 9, (7) ,   2013年, 査読有り
  • Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis., Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi ME, von Andrian UH, Chisari FV, Guidotti LG, PLoS pathogens, 7, (6) ,   2011年06月, 査読有り
  • Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection., Takahashi K, Asabe S, Wieland S, Garaigorta U, Gastaminza P, Isogawa M, Chisari FV, Proceedings of the National Academy of Sciences of the United States of America, 107, (16) 7431 - 7436,   2010年04月, 査読有り
  • Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment., Bissig KD, Wieland SF, Tran P, Isogawa M, Le TT, Chisari FV, Verma IM, The Journal of clinical investigation, 120, (3) 924 - 930,   2010年03月, 査読有り
  • Immune effectors required for hepatitis B virus clearance., Yang PL, Althage A, Chung J, Maier H, Wieland S, Isogawa M, Chisari FV, Proceedings of the National Academy of Sciences of the United States of America, 107, (2) 798 - 802,   2010年01月, 査読有り
  • A virocidal amphipathic {alpha}-helical peptide that inhibits hepatitis C virus infection in vitro., Cheng G, Montero A, Gastaminza P, Whitten-Bauer C, Wieland SF, Isogawa M, Fredericksen B, Selvarajah S, Gallay PA, Ghadiri MR, Chisari FV, Proceedings of the National Academy of Sciences of the United States of America, 105, (8) 3088 - 3093,   2008年02月, 査読有り
  • Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus., Iannacone M, Sitia G, Isogawa M, Whitmire JK, Marchese P, Chisari FV, Ruggeri ZM, Guidotti LG, Proceedings of the National Academy of Sciences of the United States of America, 105, (2) 629 - 634,   2008年01月, 査読有り
  • PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver., Maier H, Isogawa M, Freeman GJ, Chisari FV, Journal of immunology (Baltimore, Md. : 1950), 178, (5) 2714 - 2720,   2007年03月, 査読有り
  • Persistent hepatitis C virus infection in vitro: coevolution of virus and host., Zhong J, Gastaminza P, Chung J, Stamataki Z, Isogawa M, Cheng G, McKeating JA, Chisari FV, Journal of virology, 80, (22) 11082 - 11093,   2006年11月, 査読有り
  • Platelets mediate cytotoxic T lymphocyte-induced liver damage., Iannacone M, Sitia G, Isogawa M, Marchese P, Castro MG, Lowenstein PR, Chisari FV, Ruggeri ZM, Guidotti LG, Nature medicine, 11, (11) 1167 - 1169,   2005年11月, 査読有り
  • Oscillating CD8(+) T cell effector functions after antigen recognition in the liver., Isogawa M, Furuichi Y, Chisari FV, Immunity, 23, (1) 53 - 63,   2005年07月, 査読有り
  • Toll-like receptor signaling inhibits hepatitis B virus replication in vivo., Isogawa M, Robek MD, Furuichi Y, Chisari FV, Journal of virology, 79, (11) 7269 - 7272,   2005年06月, 査読有り
  • Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune responses in mice and woodchucks., Lu M, Isogawa M, Xu Y, Hilken G, Journal of virology, 79, (10) 6368 - 6376,   2005年05月, 査読有り
  • Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen., Isogawa M, Kakimi K, Kamamoto H, Protzer U, Chisari FV, Virology, 333, (2) 293 - 300,   2005年03月, 査読有り
  • Mutant hepatitis B virus surface antigens (HBsAg) are immunogenic but may have a changed specificity., Zheng X, Weinberger KM, Gehrke R, Isogawa M, Hilken G, Kemper T, Xu Y, Yang D, Jilg W, Roggendorf M, Lu M, Virology, 329, (2) 454 - 464,   2004年11月, 査読有り
  • MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs., Sitia G, Isogawa M, Iannacone M, Campbell IL, Chisari FV, Guidotti LG, The Journal of clinical investigation, 113, (8) 1158 - 1167,   2004年04月, 査読有り
  • Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes., Sitia G, Isogawa M, Kakimi K, Wieland SF, Chisari FV, Guidotti LG, Proceedings of the National Academy of Sciences of the United States of America, 99, (21) 13717 - 13722,   2002年10月, 査読有り
  • Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections., Kakimi K, Isogawa M, Chung J, Sette A, Chisari FV, Journal of virology, 76, (17) 8609 - 8620,   2002年09月, 査読有り


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