AOKI Rena

Researcher Information

Research Areas

• Life sciences / Neuroscience - general
• Life sciences / Tumor biology
• Life sciences / Developmental biology
• Life sciences / Medical biochemistry
• Life sciences / Tumor biology
• Life sciences / Cell biology

Academic & Professional Experience

• 2026/04 - Today  Nagoya City UniversityGraduate School of ScienceSpecially Appointed Assistant Professor (Part-time)

Education

• 2015/04 - 2017/03  大阪大学大学院  医学系研究科  分子病態医学専攻 博士課程
• 2013/03 - 2015/03  大阪大学大学院  医学系研究科  医科学専攻 修士課程

Published Papers

• Ouabain Suppresses CD63 Loading into Extracellular Vesicles via Na+/K+-ATPase-Dependent Localization to Autophagosomes.

  Haruki Adachi; Takeshi Yoshida; Reina E Itoh; Chitose Oneyama

  Biological & pharmaceutical bulletin 49 (2) 291 - 300 2026
• MEK/ERK‐mediated oncogenic signals promote secretion of extracellular vesicles by controlling lysosome function

  Tomoya Hikita; Ryo Uehara; Reina E. Itoh; Fumie Mitani; Mamiko Miyata; Takuya Yoshida; Rui Yamaguchi; Chitose Oneyama

  Cancer Science Wiley 113 (4) 1264 - 1276 1347-9032 2022/04 [Refereed]
  
• Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction

  Reina E. Ito; Chitose Oneyama; Kazuhiro Aoki

  PLOS ONE Public Library of Science (PLoS) 16 (4) e0249388 - e0249388 1932-6203 2021/04 [Refereed]
  
• Propagating Wave of ERK Activation Orients Collective Cell Migration

  Kazuhiro Aoki; Yohei Kondo; Honda Naoki; Toru Hiratsuka; Reina E. Itoh; Michiyuki Matsuda

  DEVELOPMENTAL CELL 43 (3) 305 - + 1534-5807 2017/11 [Refereed]
  
• Age-dependent deterioration of locomotion in Drosophila melanogaster deficient in the homologue of amyotrophic lateral sclerosis 2

  Yuta Takayama; Reina E. Itoh; Taiichi Tsuyama; Tadashi Uemura

  GENES TO CELLS 19 (6) 464 - 477 1356-9597 2014/06 [Refereed]
  
• Phosphorylation and activation of the Rac1 and Cdc42 GEF Asef in A431 cells stimulated by EGF

  Reina E. Itoh; Etsuko Kiyokawa; Kazuhiro Aoki; Teruko Nishioka; Tetsu Akiyama; Michiyuki Matsuda

  JOURNAL OF CELL SCIENCE 121 (16) 2635 - 2642 0021-9533 2008/08 [Refereed]
  
• The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src

  Norikazu Yamana; Yoshiki Arakawa; Tomohiro Nishino; Kazuo Kurokawa; Masahiro Tanji; Reina E. Itoh; James Monypenny; Toshimasa Ishizaki; Haruhiko Bito; Kazuhiko Nozaki; Nobuo Hashimoto; Michiyuki Matsuda; Shuh Narumiya

  MOLECULAR AND CELLULAR BIOLOGY 26 (18) 6844 - 6858 0270-7306 2006/09 [Refereed]
  
• Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes

  A Fujioka; K Terai; RE Itoh; K Aoki; T Nakamura; S Kuroda; E Nishida; M Matsuda

  JOURNAL OF BIOLOGICAL CHEMISTRY 281 (13) 8917 - 8926 0021-9258 2006/03 [Refereed]
  
• A FRET-based probe for epidermal growth factor receptor bound non-covalently to a pair of synthetic amphipathic helixes

  RE Itoh; K Kurokawa; A Fujioka; A Sharma; BJ Mayer; M Matsuda

  EXPERIMENTAL CELL RESEARCH 307 (1) 142 - 152 0014-4827 2005/07 [Refereed]
  
• Coactivation of Rad1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor

  K Kurokawa; RE Itoh; H Yoshizaki; Y Ohba; T Nakamura; M Matsuda

  MOLECULAR BIOLOGY OF THE CELL 15 (3) 1003 - 1010 1059-1524 2004/03 [Refereed]
  
• Activity of Rho-family GTPases during cell division as visualized with FRET-based probes

  H Yoshizaki; Y Ohba; K Kurokawa; RE Itoh; T Nakamura; N Mochizuki; K Nagashima; M Matsuda

  JOURNAL OF CELL BIOLOGY 162 (2) 223 - 232 0021-9525 2003/07 [Refereed]
  
• Activation of Rac and Cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

  RE Itoh; K Kurokawa; Y Ohba; H Yoshizaki; N Mochizuki; M Matsuda

  MOLECULAR AND CELLULAR BIOLOGY 22 (18) 6582 - 6591 0270-7306 2002/09 [Refereed]
  

Books etc

• 生きた細胞内で分子の機能を可視化する蛍光共鳴エネルギー移動を利用した新しいプローブ群

  伊藤玲奈; 松田道行 分子細胞治療、先端医学社 2003

Conference Activities & Talks

• 上皮ダイナミクスにおける Rac1 活性のイメージング  [Invited]

  伊藤 玲奈

  日本分子生物学会第36回(2013年)年会  2013/12

Other link

researchmap

https://researchmap.jp/Reina_itoh