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MANABE Tatsuya
Specially Appointed Assistant Professor
Researcher Information
Degree
Research funding number
ORCID ID
J-Global ID
Research Interests
Research Areas
Academic & Professional Experience
Education
Association Memberships
Published Papers
Books etc
Conference Activities & Talks
Misc
Research Grants & Projects
Teaching Experience
Last Updated :2024/07/05
Researcher Information
Degree
PhD in Experimental Medicine(2021/08 University of Bonn)
MSc in Dementia(2017/11 UCL)
BSc in Neuroscience(2016/07 King's College London)
Research funding number
60944006
ORCID ID
https://orcid.org/0000-0002-1424-5688
J-Global ID
202101007838191175
Research Interests
敗血症 神経原線維変化 アミロイドβ 敗血症脳症 マイクログリア インフラマソーム 細胞老化 全身性炎症 神経炎症 神経変性疾患 タウ アルツハイマー病
Research Areas
Life sciences / Neuroscience - general
Life sciences / Neurology
Life sciences / Immunology
Life sciences / Neuropathology
Academic & Professional Experience
2021/10 - Today 名古屋市立大学 大学院医学研究科脳神経科学研究所 認知症科学分野特任助教
2017/11 - 2021/07 University of Bonn Medical CenterDepartment of Neurodegenerative Diseases and Geriatric PsychiatryResearch assistant
Education
2017/11 - 2021/08 University of Bonn Faculty of Medicine
2016/09 - 2017/11 University College London UCL Queen Square Institute of Neurology
2014/09 - 2016/07 King's College London Faculty of Life Sciences and Medicine
Association Memberships
日本認知症学会 The Japan Neuroscience Society
Published Papers
Multifactorial glial responses and their contributions to AD continuum
Masanori Hijioka; Tatsuya Manabe; Takashi Saito
Clinical and Experimental Neuroimmunology Wiley 14 (2) 82 - 91 1759-1961 2023/02
[Refereed][Invited]
Cerebral dysfunctions caused by sepsis during ageing
Tatsuya Manabe; Michael T. Heneka
Nature Reviews Immunology Springer Science and Business Media LLC 22 (7) 444 - 458 1474-1733 2022/07
[Refereed]
Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing
Tatsuya Manabe; Ildikó Rácz; Stephanie Schwartz; Linda Oberle; Francesco Santarelli; Julius V. Emmrich; Jonas J. Neher; Michael T. Heneka
Journal of Neurochemistry Wiley 159 (3) 525 - 542 0022-3042 2021/08
[Refereed]
Books etc
医学のあゆみ:アルツハイマー病 ─研究と治療の最前線
眞鍋達也; 齊藤貴志 (Contributorアルツハイマー病のモデル開発 ─前臨床モデルから臨床モデルへ)医歯薬出版 2023/12 909–915
実験医学増刊:いま新薬で加速する神経変性疾患研究 ー 異常タンパク質の構造、凝集のしくみから根本治療の真の標的に迫る
眞鍋達也; 齊藤貴志 (Contributorアルツハイマー病の動物モデルの現状と今後の展望)羊土社 2023/07 9784758104128 225 137–143
Conference Activities & Talks
Chronic kidney disease elevating tau phosphorylation in the aged mouse brain
Manabe, T; Iida, T; Saito, T
Neuro2024 2024/07
Systemic inflammation challenging the ageing brains
Manabe, T; Saito, T; Heneka, M.T
The 128th Annual Meeting of the Japanese Association of Anatomists 2023/03
Study of systemic inflammation and its potential effect on glial senescence during ageing
[Invited]
Manabe, T
The 26th Annual Meeting of the Japan Glia 2022/12
タウ性状に対する腸内細菌の影響-野生型マウスでの解析-
Aoki, S; Takagi, T; Hijioka, M; Manabe, T; Dohi, N; Asamitsu, K; Saito, T
第41回認知症学会学術集会 2022/11
Reversibility of tau hyperphosphorylation in response to hypothermia
Takagi, T; Manabe, T; Dohi, N; Hijioka, M; Saito, T
第41回認知症学会学術集会 2022/11
全身性炎症後に起こる認知機能低下の機構とミクログリアの関与
Tatsuya Manabe
第24回 IBSセミナー 2022/10 名古屋市立大学
Vulnerability of CA3 excitatory synapses in the middle-aged brain in response to systemic inflammation
[Invited]
Manabe, T
Memory Research Seminar (OIST) 2022
Delayed reduction of excitatory synapses in CA3 following systemic inflammation.
Manabe, T; Rácz, I; Schwartz, S; Santarelli, F; Emmrich, J.V; Neher, J.J; Heneka, M.T
Neuro2022 2022
CA3 excitatory synapse loss as a chronic effect of septic shock in middle-aged mice.
Manabe, T; Rácz, I; Schwartz, S; Santarelli, F; Emmrich, J.V; Neher, J.J; Heneka, M.T
Alzheimer's Association International Conference (AAIC) 2021 2021
Investigation of microglia-neuron interactions in response to septic shock
Manabe, T; Rácz, I; Schwartz, S; Neher, J.J; Emmrich, J.V; Heneka, M.T
Venusberg Meeting on Neuroinflammation 2019
Investigation of microglia-neuron interactions in response to septic shock.
Manabe, T; Rácz, I; Schwartz, S; Neher, J.J; Emmrich, J.V; Heneka, M.T
Clusters Science Day 2019
MISC
CA3 excitatory synapse loss as a chronic effect of septic shock in middle-aged mice
Tatsuya Manabe; Ildikó Rácz; Stephanie Schwartz; Francesco Santarelli; Julius V. Emmrich; Jonas J. Neher; Michael T. Heneka Alzheimer's & Dementia 17- (e052228) 2022/02
Research Grants & Projects
アルツハイマー病と慢性腎臓病における血漿中リン酸化タウ上昇の機序の解明
日本学術振興会:
科学研究費助成事業
Date (from‐to) :
2024/04 -2027/03
Author :
眞鍋 達也
アルツハイマー病と慢性腎臓病モデルマウスの血漿解析に基づく疾患類似性と連関の探索
名古屋市立大学:
令和5年度 特別研究奨励費
Date (from‐to) :
2023/06 -2024/03
Author :
眞鍋達也
Recapitulation of tau pathology and its relevance with renal failure in mouse models of Alzheimer's disease
Japan Society for the Promotion of Science:
Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up
Date (from‐to) :
2022/08 -2024/03
Author :
眞鍋 達也
Teaching Experience
Advanced Brain Science; Brain ScienceAdvanced Brain Science; Brain Science Nagoya City University Current Research in Alzheimer’s Disease
基礎自主研修基礎自主研修 Nagoya City University
学術論文入門学術論文入門 Nagoya City University
Other link
researchmap
https://researchmap.jp/tatsuya_manabe