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MANABE Tatsuya

    Specially Appointed Assistant Professor
Last Updated :2025/06/15

Researcher Information

Degree

  • PhD in Experimental Medicine（2021/08 University of Bonn）
  • MSc in Dementia（2017/11 UCL）
  • BSc in Neuroscience（2016/07 King's College London）

Research funding number

  • 60944006

ORCID ID

J-Global ID

Research Interests

  • 敗血症   神経原線維変化   アミロイドβ   敗血症脳症   マイクログリア   インフラマソーム   細胞老化   全身性炎症   神経炎症   神経変性疾患   タウ   アルツハイマー病   

Research Areas

  • Life sciences / Neuroscience - general
  • Life sciences / Neurology
  • Life sciences / Immunology
  • Life sciences / Neuropathology

Academic & Professional Experience

  • 2021/10 - Today  名古屋市立大学 大学院医学研究科脳神経科学研究所 認知症科学分野特任助教
  • 2017/11 - 2021/07  University of Bonn Medical CenterDepartment of Neurodegenerative Diseases and Geriatric PsychiatryResearch assistant

Education

  • 2017/11 - 2021/08  University of Bonn  Faculty of Medicine
  • 2016/09 - 2017/11  University College London  UCL Queen Square Institute of Neurology
  • 2014/09 - 2016/07  King's College London  Faculty of Life Sciences and Medicine

Association Memberships

  • 日本認知症学会   The Japan Neuroscience Society   

Published Papers

Books etc

Conference Activities & Talks

  • An alternative source of elevated tau phosphorylation in plasma following renal dysfunction
    Manabe, T.; Iida, T.; Saito, T.
    Alzheimer's Association International Conference (AAIC)  2025/07
  • バイオマーカーから見た前臨床アルツハイマー病モデルマウスの妥当性
    Manabe, T.
    第4回ApoE研究会  2025/06
  • Alzheimer’s disease-related tau phosphorylation status in chronic kidney disease
    Manabe, T.; Iida, T.; Saito, T.
    6th Japan-UK Neuroscience Symposium  2025/01
  • Novel kidney-brain axis illuminated by chronic kidney disease and ageing
    Manabe, T; Iida, T; Saito, T
    The 43rd annual meeting of Japan society for dementia research  2024/11
  • Chronic kidney disease elevating tau phosphorylation in the aged mouse brain
    Manabe, T; Iida, T; Saito, T
    Neuro2024  2024/07
  • Systemic inflammation challenging the ageing brains
    Manabe, T; Saito, T; Heneka, M.T
    The 128th Annual Meeting of the Japanese Association of Anatomists  2023/03
  • Study of systemic inflammation and its potential effect on glial senescence during ageing  [Invited]
    Manabe, T
    The 26th Annual Meeting of the Japan Glia  2022/12
  • タウ性状に対する腸内細菌の影響-野生型マウスでの解析-
    Aoki, S; Takagi, T; Hijioka, M; Manabe, T; Dohi, N; Asamitsu, K; Saito, T
    第41回認知症学会学術集会  2022/11
  • Reversibility of tau hyperphosphorylation in response to hypothermia
    Takagi, T; Manabe, T; Dohi, N; Hijioka, M; Saito, T
    第41回認知症学会学術集会  2022/11
  • 全身性炎症後に起こる認知機能低下の機構とミクログリアの関与
    Tatsuya Manabe
    第24回 IBSセミナー  2022/10  名古屋市立大学
  • Vulnerability of CA3 excitatory synapses in the middle-aged brain in response to systemic inflammation  [Invited]
    Manabe, T
    Memory Research Seminar (OIST)  2022
  • Delayed reduction of excitatory synapses in CA3 following systemic inflammation.
    Manabe, T; Rácz, I; Schwartz, S; Santarelli, F; Emmrich, J.V; Neher, J.J; Heneka, M.T
    Neuro2022  2022
  • CA3 excitatory synapse loss as a chronic effect of septic shock in middle-aged mice.
    Manabe, T; Rácz, I; Schwartz, S; Santarelli, F; Emmrich, J.V; Neher, J.J; Heneka, M.T
    Alzheimer's Association International Conference (AAIC) 2021  2021
  • Investigation of microglia-neuron interactions in response to septic shock
    Manabe, T; Rácz, I; Schwartz, S; Neher, J.J; Emmrich, J.V; Heneka, M.T
    Venusberg Meeting on Neuroinflammation  2019
  • Investigation of microglia-neuron interactions in response to septic shock.
    Manabe, T; Rácz, I; Schwartz, S; Neher, J.J; Emmrich, J.V; Heneka, M.T
    Clusters Science Day  2019

MISC

Research Grants & Projects

  • 日本学術振興会：科学研究費助成事業
    Date (from‐to) : 2024/04 -2027/03 
    Author : 眞鍋 達也
  • ヒト化タウノックインマウスを用いたアルツハイマー病における血中リン酸化タウ蓄積の解明
    日東学術振興財団：第41回研究助成
    Date (from‐to) : 2024/12 -2026/12 
    Author : 眞鍋達也
  • 高齢 CKD マウス脳における⻑期的なタウのリン酸化への影響
    神戸医療産業推進機構：第5回NBRP加齢マウス供給事業
    Date (from‐to) : 2024/09 -2025/03 
    Author : 眞鍋達也
  • 慢性腎臓病で見られる血中リン酸化タウ蓄積の解明
    愛知腎臓財団：令和6年度研究助成
    Date (from‐to) : 2024/08 -2025/03 
    Author : 眞鍋達也
  • アルツハイマー病と慢性腎臓病モデルマウスの血漿解析に基づく疾患類似性と連関の探索
    名古屋市立大学：令和5年度 特別研究奨励費
    Date (from‐to) : 2023/06 -2024/03 
    Author : 眞鍋達也
  • Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up
    Date (from‐to) : 2022/08 -2024/03 
    Author : 眞鍋 達也

Teaching Experience

  • Advanced Brain Science; Brain ScienceAdvanced Brain Science; Brain Science Nagoya City University Current Research in Alzheimer’s Disease
  • 基礎自主研修基礎自主研修 Nagoya City University
  • 学術論文入門学術論文入門 Nagoya City University

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