2025/08 Xi'an International Organization for Crystal Growth, Chinese Ceramic Society (CCS), Northwestern Polytechnical University, Chinese Association for Crystal Growth, CCS
(M07)
Evaluate the pH dependence of calcium phosphate crystal phase transformation for elucidating the process of kidney stone formation [Not invited]
21st International Conference on Crystal Growth and Epitaxy (ICCGE-21) 2025/08 Xi'an International Organization for Crystal Growth, Chinese Ceramic Society (CCS), Northwestern Polytechnical University, Chinese Association for Crystal Growth, CCS
(M05)
Prediction of Urolithiasis Recurrence Based on Urinary Crystallization Tendencies [Not invited]
21st International Conference on Crystal Growth and Epitaxy (ICCGE-21) 2025/08 Xi'an International Organization for Crystal Growth, Chinese Ceramic Society (CCS), Northwestern Polytechnical University, Chinese Association for Crystal Growth, CCS
(M04)
Elucidating the in vivo Mechanism of Calcium Phosphate Crystal Formation in the Early Stage of Kidney Stone Formation [Not invited]
21st International Conference on Crystal Growth and Epitaxy (ICCGE-21) 2025/08 Xi'an International Organization for Crystal Growth, Chinese Ceramic Society (CCS), Northwestern Polytechnical University, Chinese Association for Crystal Growth, CCS
(M03)
Preliminary study on the growth enhancement of calcium oxalate crystals using focused laser beam [Not invited]
The 9th International Congress on Laser Advanced Materials Processing (LAMP2025) 2025/06 Ise-city, Mie-prefecture, Japan Japan Laser Processing Society
p-84
Triggering Kidney Stone Growth: Calcium Phosphate Crystals as Accelerators of Calcium Oxalate Monohydrate Formation [Not invited]
Dynamic observation of polymorphic phase transition of calcium oxalate crystals; A novel system to elucidate the process and kinetics of urinary stones formation [Not invited]
International Conference on Crystal Growth and Epitaxy (ICCGE20) 2023/08 Naples Italy International Conference on Crystal Growth and Epitaxy
Validating the theory of phase transition from calcium oxalate dihydrate to monohydrate in the stone formation: the first artificial in vivo experiment [Not invited]
Elucidating the in vivo effects of calcium-binding proteins on crystal growth using a novel multifaceted structure analysis of human kidney stones [Not invited]
BCG膀胱注入療法の1年後に診断された感染性大動脈瘤の経験と文献考察(An experience of the infectious aortic aneurysm diagnosed one year after the BCG bladder instillation therapy and the literature review)
2022/07 日本尿路結石症学会 日本尿路結石症学会 第32回学術集会 学会賞 Multicolor imaging of calcium-binding proteins in human kidney stones for elucidating the effects of proteins on crystal growth JPN japan_society
Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory)
Date (from‐to) : 2019/06 -2022/03
Author : Mihoko Maruyama
We revealed micro-scale distributions of three different proteins, osteopontin (OPN), renal prothrombin fragment 1 (RPTF-1), and calgranulin A (Cal-A), in human kidney stones retaining original mineral phases and textures: calcium oxalate monohydrate (COM) and calcium oxalate dihydrate (COD). OPN and RPTF-1 were distributed inside of both COM and COD crystals, whereas Cal-A was distributed outside of crystals. OPN and RPTF-1 showed homogeneous distributions in COM crystals with mosaic texture, and periodically distributions parallel to specific crystal faces in COD crystals. The unique distributions of these proteins enable us to interpret the different in vivo effects of each protein on CaOx crystal growth based on their physico-chemical properties and the complex physical environment changes of each protein. This method will further allow us to elucidate in vivo effects of different proteins on kidney stone formation.