Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Date (from‐to) : 2015/04 -2018/03
Author : Tsukamoto Takeshi
We investigated the mechanism of inflammatory response after trauma using ''Two-hit model".
Two-hit model consists of tissue-bone matrix (TBX) model and hemorrhagic shock model. TBX model is a novel model, we developed before.
TBX induced a systematic inflammatory response and attenuated a intestinal motility at 21 hours after transplantation of TBX. However "Tow-hit model" did not induced inflammatory response in our experiment.