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野崎 実穂ノザキ ミホ

所属部署医学研究科視覚科学分野
職名講師
メールアドレス
ホームページURLhttp://www.med.nagoya-cu.ac.jp/ganka.dir/index.html
生年月日
Last Updated :2019/07/06

研究者基本情報

学歴

  •  - 1993年, 名古屋市立大学, 医学部, 医学科

学位

  • 博士(医学), 名古屋市立大学

所属学協会

  • 日本眼科学会
  • 小児眼科学会
  • 日本糖尿病眼学会
  • 日本眼科手術学会

研究活動情報

研究分野

  • 外科系臨床医学, 眼科学

研究キーワード

    血管新生, 加齢黄斑変性, 血管内皮増殖因子, 糖尿病網膜症

論文

  • Suppression of Retinal Neovascularization by Anti-CCR3 Treatment in an Oxygen-Induced Retinopathy Model in Mice., Hirahara S, Nozaki M, Ohbayashi M, Hasegawa N, Ozone D, Ogura Y, Ophthalmic research, 58, (1) 56 - 66,   2017年, 査読有り
  • Less Expansion of Short-Pulse Laser Scars in Panretinal Photocoagulation for Diabetic Retinopathy., Higaki M, Nozaki M, Yoshida M, Ogura Y, Journal of ophthalmology, 2018,   2018年, 査読有り
  • Tissue Plasminogen Activator as an Antiangiogenic Agent in Experimental Laser-Induced Choroidal Neovascularization in Mice., Ozone D, Mizutani T, Nozaki M, Ohbayashi M, Hasegawa N, Kato A, Yasukawa T, Ogura Y, Investigative ophthalmology & visual science, 57, (13) 5348 - 5354,   2016年10月, 査読有り
  • Evaluation of Navigated Laser Photocoagulation (Navilas 577+) for the Treatment of Refractory Diabetic Macular Edema., Kato F, Nozaki M, Kato A, Hasegawa N, Morita H, Yoshida M, Ogura Y, Journal of ophthalmology, 2018,   2018年, 査読有り
  • Characteristics of Polypoidal Choroidal Vasculopathy Evaluated by Optical Coherence Tomography Angiography., Tomiyasu T, Nozaki M, Yoshida M, Ogura Y, Investigative ophthalmology & visual science, 57, (9) OCT324 - 30,   2016年07月, 査読有り
  • New Insights Into Microaneurysms in the Deep Capillary Plexus Detected by Optical Coherence Tomography Angiography in Diabetic Macular Edema., Hasegawa N, Nozaki M, Takase N, Yoshida M, Ogura Y, Investigative ophthalmology & visual science, 57, (9) OCT348 - 55,   2016年07月, 査読有り
  • Densitometry of Choroidal Vessels in Eyes With and Without Central Serous Chorioretinopathy by Wide-Field Indocyanine Green Angiography., Hirahara S, Yasukawa T, Kominami A, Nozaki M, Ogura Y, American journal of ophthalmology, 166, 103 - 111,   2016年06月, 査読有り
  • Value of OCT Angiography in the Diagnosis of Choroidal Neovascularization Complicating Multiple Evanescence White Dot Syndrome., Nozaki M, Hamada S, Kimura M, Yoshida M, Ogura Y, Ophthalmic surgery, lasers & imaging retina, 47, (6) 580 - 584,   2016年06月, 査読有り
  • [Diabetic macular edema--pathogenesis, diagnosis and treatment]., Nozaki M, Nihon rinsho. Japanese journal of clinical medicine, 74 Suppl 2, 140 - 147,   2016年04月, 査読有り
  • ENLARGEMENT OF FOVEAL AVASCULAR ZONE IN DIABETIC EYES EVALUATED BY EN FACE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY., Takase N, Nozaki M, Kato A, Ozeki H, Yoshida M, Ogura Y, Retina (Philadelphia, Pa.), 35, (11) 2377 - 2383,   2015年11月, 査読有り
  • Human IgG1 antibodies suppress angiogenesis in a target-independent manner., Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J, Signal transduction and targeted therapy, 1,   2016年, 査読有り
  • [Evaluation of Diabetic Retinopathy with Ultra-wide Field Fluorescein Angiography]., Tomiyasu T, Hirahara S, Nozaki M, Yoshida M, Ogura Y, Nippon Ganka Gakkai zasshi, 119, (11) 807 - 811,   2015年11月, 査読有り
  • Wide-field optical coherence tomography angiography using extended field imaging technique to evaluate the nonperfusion area in retinal vein occlusion., Kimura M, Nozaki M, Yoshida M, Ogura Y, Clinical ophthalmology (Auckland, N.Z.), 10, 1291 - 1295,   2016年, 査読有り
  • Vitrectomy without gas tamponade for macular retinoschisis associated with normal-tension glaucoma., Orazbekov L, Yasukawa T, Hirano Y, Ogura S, Usui H, Nozaki M, Ogura Y, Ophthalmic surgery, lasers & imaging retina, 46, (1) 107 - 110,   2015年01月, 査読有り
  • [Comparison of outcomes of conventional laser versus pascal laser for diabetic retinopathy]., Yamakawa M, Nozaki M, Sato R, Morita H, Yoshida M, Ogura Y, Nippon Ganka Gakkai zasshi, 118, (4) 362 - 367,   2014年04月, 査読有り
  • Suppression of laser-induced choroidal neovascularization by a CCR3 antagonist., Mizutani T, Ashikari M, Tokoro M, Nozaki M, Ogura Y, Investigative ophthalmology & visual science, 54, (2) 1564 - 1572,   2013年02月, 査読有り
  • Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation., Itaya M, Sakurai E, Nozaki M, Yamada K, Yamasaki S, Asai K, Ogura Y, Investigative ophthalmology & visual science, 48, (12) 5677 - 5683,   2007年12月, 査読有り
  • Efficient delivery of siRNA by atelocollagen in a murine laser-induced choroidal neovascularization model., Ito Y, Nozaki M, Sugitani K, Ashikari M, Hirano Y, Ogura Y, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 230, (4) 215 - 221,   2013年, 査読有り
  • A case of retinopathy of prematurity treated by pattern scan laser photocoagulation., Ota S, Nozaki M, Hirahara S, Hattori T, Yoshida M, Ogura Y, Clinical ophthalmology (Auckland, N.Z.), 8, 1409 - 1412,   2014年, 査読有り
  • Intravitreal ranibizumab for patients with neovascular age-related macular degeneration with good baseline visual acuity., Kato A, Yasukawa T, Suga K, Hirano Y, Nozaki M, Yoshida M, Ogura Y, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 233, (1) 27 - 34,   2015年, 査読有り
  • Corneal avascularity is due to soluble VEGF receptor-1., Ambati BK, Nozaki M, Singh N, Takeda A, Jani PD, Suthar T, Albuquerque RJ, Richter E, Sakurai E, Newcomb MT, Kleinman ME, Caldwell RB, Lin Q, Ogura Y, Orecchia A, Samuelson DA, Agnew DW, St Leger J, Green WR, Mahasreshti PJ, Curiel DT, Kwan D, Marsh H, Ikeda S, Leiper LJ, Collinson JM, Bogdanovich S, Khurana TS, Shibuya M, Baldwin ME, Ferrara N, Gerber HP, De Falco S, Witta J, Baffi JZ, Raisler BJ, Ambati J, Nature, 443, (7114) 993 - 997,   2006年10月, 査読有り
  • Short pulse laser induces less inflammatory cytokines in the murine retina after laser photocoagulation., Ito A, Hirano Y, Nozaki M, Ashikari M, Sugitani K, Ogura Y, Ophthalmic research, 53, (2) 65 - 73,   2015年, 査読有り
  • Drusen complement components C3a and C5a promote choroidal neovascularization., Nozaki M, Raisler BJ, Sakurai E, Sarma JV, Barnum SR, Lambris JD, Chen Y, Zhang K, Ambati BK, Baffi JZ, Ambati J, Proceedings of the National Academy of Sciences of the United States of America, 103, (7) 2328 - 2333,   2006年02月, 査読有り
  • Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A., Nozaki M, Sakurai E, Raisler BJ, Baffi JZ, Witta J, Ogura Y, Brekken RA, Sage EH, Ambati BK, Ambati J, The Journal of clinical investigation, 116, (2) 422 - 429,   2006年02月, 査読有り
  • Optical coherence tomographic findings of the anterior segment after nonpenetrating deep sclerectomy., Nozaki M, Kimura H, Kojima M, Ogura Y, American journal of ophthalmology, 133, (6) 837 - 839,   2002年06月, 査読有り
  • Enhanced expression of adhesion molecules of the retinal vascular endothelium in spontaneous diabetic rats., Nozaki M, Ogura Y, Hirabayashi Y, Saishin Y, Shimada S, Ophthalmic research, 34, (3) 158 - 164,   2002年05月, 査読有り
  • Prevention of increased abnormal fundus autofluorescence with blue light-filtering intraocular lenses., Nagai H, Hirano Y, Yasukawa T, Morita H, Nozaki M, Wolf-Schnurrbusch U, Wolf S, Ogura Y, Journal of cataract and refractive surgery, 41, (9) 1855 - 1859,   2015年09月, 査読有り
  • IL-18 is not therapeutic for neovascular age-related macular degeneration., Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G, Ambati BK, Hinton DR, Ambati J, Nature medicine, 20, (12) 1372 - 1375,   2014年12月, 査読有り
  • [Preference and trends of treatment for diabetic retinopathy in Korea and Japan]., Nozaki M, Suzuma K, Inoue M, Kawasaki R, Kida T, Takamura Y, Nagaoka T, Murakami T, Yoshida S, Korea-Japan Diabetic Retinopathy Study Group., Nippon Ganka Gakkai zasshi, 117, (9) 735 - 742,   2013年09月, 査読有り
  • [Age-related macular degeneration]., Nozaki M, Nihon rinsho. Japanese journal of clinical medicine, 70 Suppl 8, 647 - 651,   2012年11月, 査読有り
  • [Pathology of diabetic retinopathy]., Nozaki M, Ogura Y, Nihon rinsho. Japanese journal of clinical medicine, 68 Suppl 9, 224 - 227,   2010年11月, 査読有り
  • Suppression of laser-induced choroidal neovascularization by nontargeted siRNA., Ashikari M, Tokoro M, Itaya M, Nozaki M, Ogura Y, Investigative ophthalmology & visual science, 51, (7) 3820 - 3824,   2010年07月, 査読有り
  • Indocyanine green angiography-guided laser photocoagulation combined with sub-Tenon's capsule injection of triamcinolone acetonide for idiopathic macular telangiectasia., Hirano Y, Yasukawa T, Usui Y, Nozaki M, Ogura Y, The British journal of ophthalmology, 94, (5) 600 - 605,   2010年05月, 査読有り
  • Intraocular pressure elevation following triamcinolone acetonide administration as related to administration routes., Hirano Y, Ito T, Nozaki M, Yasukawa T, Sakurai E, Yoshida M, Ogura Y, Japanese journal of ophthalmology, 53, (5) 519 - 522,   2009年09月, 査読有り
  • CCR3 is a target for age-related macular degeneration diagnosis and therapy., Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J, Nature, 460, (7252) 225 - 230,   2009年07月, 査読有り
  • Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth., Cho WG, Albuquerque RJ, Kleinman ME, Tarallo V, Greco A, Nozaki M, Green MG, Baffi JZ, Ambati BK, De Falco M, Alexander JS, Brunetti A, De Falco S, Ambati J, Proceedings of the National Academy of Sciences of the United States of America, 106, (17) 7137 - 7142,   2009年04月, 査読有り
  • [Incidence of posterior subcapsular cataract progression after triamcinolone acetonide administration]., Yoshimura M, Hirano Y, Nozaki M, Yoshida M, Ogura Y, Nippon Ganka Gakkai zasshi, 112, (9) 786 - 789,   2008年09月, 査読有り
  • Sequence- and target-independent angiogenesis suppression by siRNA via TLR3., Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baffi JZ, Albuquerque RJ, Yamasaki S, Itaya M, Pan Y, Appukuttan B, Gibbs D, Yang Z, Karikó K, Ambati BK, Wilgus TA, DiPietro LA, Sakurai E, Zhang K, Smith JR, Taylor EW, Ambati J, Nature, 452, (7187) 591 - 597,   2008年04月, 査読有り
  • Toward a higher fidelity model of AMD., Raisler BJ, Nozaki M, Baffi J, Hauswirth WW, Ambati J, Advances in experimental medicine and biology, 613, 185 - 192,   2008年, 査読有り
  • A case of adult limbal xanthogranuloma., Hirata M, Nozaki M, Ozeki H, Hirata F, Ogura Y, Japanese journal of ophthalmology, 51, (4) 302 - 304,   2007年07月, 査読有り
  • Tailor-made orbitocranioplasty for a sphenorbital encephalocele presenting as pulsatile exophthalmos. Case report., Katano H, Aihara N, Takeuchi Y, Nozaki M, Yamada K, Journal of neurosurgery, 106, (2 Suppl) 126 - 130,   2007年02月, 査読有り
  • [Incidence and risk factors of intraocular pressure elevation after triamcinolone acetonide administration for macular disorders]., Ito T, Nozaki M, Ogura Y, Nippon Ganka Gakkai zasshi, 110, (5) 379 - 383,   2006年05月, 査読有り
  • Suppression of laser-induced choroidal neovascularization by posterior sub-tenon administration of triamcinolone acetonide., Kato A, Kimura H, Okabe K, Okabe J, Kunou N, Nozaki M, Ogura Y, Retina (Philadelphia, Pa.), 25, (4) 503 - 509,   2005年06月, 査読有り
  • Scleral plug of biodegradable polymers containing tacrolimus (FK506) for experimental uveitis., Sakurai E, Nozaki M, Okabe K, Kunou N, Kimura H, Ogura Y, Investigative ophthalmology & visual science, 44, (11) 4845 - 4852,   2003年11月, 査読有り
  • [A case of peritoneal malignant mesothelioma]., Nozaki M, Suzuki T, Takahashi H, Nishimura S, Sakurabayashi S, Yoshino K, Hirano M, Kawauchi N, Ogawa M, Suzuki T, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 100, (5) 610 - 612,   2003年05月, 査読有り
  • Late-onset laser in situ keratomileusis (LASIK) flap dehiscence during retinal detachment surgery., Sakurai E, Okuda M, Nozaki M, Ogura Y, American journal of ophthalmology, 134, (2) 265 - 266,   2002年08月, 査読有り

MISC

  • 全身奇形を合併したPeters奇形の1例, 臨床眼科, 50,   1996年
  • 合眼症の1例, 日本眼科紀要, 47,   1996年
  • 小眼球症マウスにおける眼瞼発生過程の組織学的検索, 日本眼科学会雑誌, 102, (8) 540 - 544,   1998年
  • Nontargeted siRNA suppresses Laser -induced choroidal neovascularization

競争的資金

  • 眼先天異常の組織学的・組織化学的研究
  • 小眼球症マウスにおける眼瞼発生過程の組織学的・組織化学的研究
  • 糖尿病ラット網膜における接着分子
  • 加齢黄斑変性の病態解明
  • 網膜中心窩はなぜ無血管なのか
  • siRNAによる非特異的血管新生抑制


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