研究者データベース
山崎 小百合ヤマザキ サユリ
| 所属部署 | 医学研究科免疫学分野 |
|---|---|
| 職名 | 教授 |
| メールアドレス | |
| ホームページURL | http://www.med.nagoya-cu.ac.jp/immunol.dir/ |
| 生年月日 |
Last Updated :2019/04/20
研究者基本情報
学歴
- 1991年04月 - 1995年03月, 東京医科歯科大学, 医学部大学院
- 1985年04月 - 1991年03月, 東京医科歯科大学, 医学部
学位
- 医学, 東京医科歯科大学
経歴
- 2014年12月 - 現在, 名古屋市立大学大学院, 医学研究科 免疫学, 教授
- 2012年04月 - 2014年11月, 名古屋市立大学大学院, 医学研究科 加齢環境皮膚科学, 准教授
- 2011年04月 - 2012年03月, 獨協医科大学越谷病院, 皮膚科, 講師
- 2011年04月 - 2012年03月, 東京医科歯科大学, 皮膚科, 非常勤講師
- 2009年07月 - 2011年03月, 北海道大学大学院, 医学研究科 免疫学, 特任准教授
- 2009年06月 - 2009年06月, 米国ロックフェラー大学, Research Assistant Professor
- 2001年08月 - 2009年05月, 米国ロックフェラー大学, Research Associate (Instructor)
- 1999年04月 - 2001年07月, 京都大学再生医科学研究所, 日本学術振興会特別研究員
- 1998年07月 - 1999年03月, 東京都老人総合研究所, 免疫病理部門, 客員研究員
- 1995年04月 - 1998年06月, 東京医科歯科大学皮膚科関連病院ローテーション
研究活動情報
研究分野
- 基礎医学, 免疫学
研究キーワード
- 樹状細胞, 免疫制御, 制御性T細胞
論文
- Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer., Matoba T, Imai M, Ohkura N, Kawakita D, Ijichi K, Toyama T, Morita A, Murakami S, Sakaguchi S, Yamazaki S, Int J Cancer, 2018年11月
- Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells. iScience., Loh JT, Lim TJF, Ikumi K, Matoba T, Janela B, Gunawan M, Toyama T, Bunjamin M, Ng LG, Poidinger M, Morita A, Ginhoux F, Yamazaki S, Lam KP, Su IH, iScience, 10, 23 - 39, 2018年11月
- Ultraviolet B-induced maturation of CD11b-Type Langerin2dendritic cells controls the expansion of foxp3+regulatory t cells in the skin, Sayuri Yamazaki, Mizuyu Odanaka, Akiko Nishioka, Saori Kasuya, Hiroaki Shime, Hiroaki Hemmi, Hiroaki Hemmi, Masaki Imai, Dieter Riethmacher, Dieter Riethmacher, Tsuneyasu Kaisho, Tsuneyasu Kaisho, Naganari Ohkura, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita, Journal of Immunology, 200, 119 - 129, 2018年01月
- Bath-PUVA therapy improves impaired resting regulatory T cells and increases activated regulatory T cells in psoriasis, Ryoji Kubo, Shinnosuke Muramatsu, Yoko Sagawa, Chiyo Saito, Saori Kasuya, Akiko Nishioka, Emi Nishida, Sayuri Yamazaki, Akimichi Morita, Journal of Dermatological Science, 86, 46 - 53, 2017年04月
- The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin, Merry Gunawan, Nandini Venkatesan, Jia Tong Loh, Jong Fu Wong, Heidi Berger, Wen Hao Neo, Liang Yao Jackson Li, Myint Khun La Win, Yin Hoe Yau, Tiannan Guo, Peter Chi Ee See, Sayuri Yamazaki, Keh Chuang Chin, Keh Chuang Chin, Alexandre R. Gingras, Susana Geifman Shochat, Lai Guan Ng, Siu Kwan Sze, Florent Ginhoux, I. Hsin Su, Nature Immunology, 16, 505 - 516, 2015年01月
- Homeostasis of thymus-derived Foxp3+regulatory T cells is controlled by ultraviolet B exposure in the skin, Sayuri Yamazaki, Akiko Nishioka, Saori Kasuya, Naganari Ohkura, Hiroaki Hemmi, Tsuneyasu Kaisho, Tsuneyasu Kaisho, Osamu Taguchi, Osamu Taguchi, Shimon Sakaguchi, Akimichi Morita, Journal of Immunology, 193, 5488 - 5497, 2014年12月
- Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease, Yoshinaga Ito, Motomu Hashimoto, Motomu Hashimoto, Motomu Hashimoto, Motomu Hashimoto, Keiji Hirota, Naganari Ohkura, Naganari Ohkura, Hiromasa Morikawa, Hiroyoshi Nishikawa, Atsushi Tanaka, Atsushi Tanaka, Moritoshi Furu, Moritoshi Furu, Hiromu Ito, Hiromu Ito, Takao Fujii, Takao Fujii, Takashi Nomura, Sayuri Yamazaki, Akimichi Morita, Dario A.A. Vignali, Dario A.A. Vignali, John W. Kappler, John W. Kappler, Shuichi Matsuda, Tsuneyo Mimori, Noriko Sakaguchi, Shimon Sakaguchi, Shimon Sakaguchi, Shimon Sakaguchi, Science, 346, 363 - 368, 2014年10月
- Antigen delivery to CD11c+CD8-dendritic cells induces protective immune responses against experimental melanoma in mice in vivo, Kirsten Neubert, Christian H.K. Lehmann, Lukas Heger, Anna Baranska, Anna Maria Staedtler, Veit R. Buchholz, Sayuri Yamazaki, Gordon F. Heidkamp, Nathalie Eissing, Henry Zebroski, Michel C. Nussenzweig, Falk Nimmerjahn, Diana Dudziak, Journal of Immunology, 192, 5830 - 5838, 2014年06月
- Dendritic cells in the periphery control antigen-specific natural and induced regulatory T cells, Sayuri Yamazaki, Akimichi Morita, Frontiers in Immunology, 4, 2013年09月
- Photo(chemo)therapy Reduces Circulating Th17 Cells and Restores Circulating Regulatory T Cells in Psoriasis, Takuya Furuhashi, Chiyo Saito, Kan Torii, Emi Nishida, Sayuri Yamazaki, Akimichi Morita, PLoS ONE, 8, 2013年01月
- Dendritic Cells from Oral Cavity Induce Foxp3+Regulatory T Cells upon Antigen Stimulation, Sayuri Yamazaki, Sayuri Yamazaki, Akira Maruyama, Kohei Okada, Misako Matsumoto, Akimichi Morita, Tsukasa Seya, PLoS ONE, 7, 2012年12月
- Treatment of advanced tumors with agonistic anti-GITR mab and its effects on tumor-infiltrating Foxp3 +CD25 +CD4 + regulatory T cells, Kuibeom Ko, Sayuri Yamazaki, Kyoko Nakamura, Tomohisa Nishioka, Keiji Hirota, Tomoyuki Yamaguchi, Jun Shimizu, Takashi Nomura, Tsutomu Chiba, Shimon Sakaguchi, Journal of Experimental Medicine, 209, 423 - 423, 2012年02月01日
- Tlr2-dependent induction of il-10 and foxp3+cd25+cd4+ regulatory t cells prevents effective anti-tumor immunity induced by pam2 lipopeptides in vivo, Sayuri Yamazaki, Kohei Okada, Akira Maruyama, Misako Matsumoto, Hideo Yagita, Tsukasa Seya, PLoS ONE, 6, 2011年05月
- Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2, Ryoko Sawahata, Hiroaki Shime, Sayuri Yamazaki, Norimitsu Inoue, Takashi Akazawa, Yukari Fujimoto, Koichi Fukase, Misako Matsumoto, Tsukasa Seya, Microbes and Infection, 13, 350 - 358, 2011年04月
- The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation, Masahiro Azuma, Ryoko Sawahata, Yuusuke Akao, Yuusuke Akao, Takashi Ebihara, Takashi Ebihara, Sayuri Yamazaki, Misako Matsumoto, Masahito Hashimoto, Koichi Fukase, Yukari Fujimoto, Tsukasa Seya, PLoS ONE, 5, 1 - 12, 2010年11月
- Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells, Sayuri Yamazaki, Ralph M. Steinman, Journal of Dermatological Science, 54, 69 - 75, 2009年05月
- CD80+CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells, Sayuri Yamazaki, Diana Dudziak, Diana Dudziak, Gordon F. Heidkamp, Gordon F. Heidkamp, Christopher Fiorese, Anthony J. Bonito, Kayo Inaba, Kayo Inaba, Michel C. Nussenzweig, Ralph M. Steinman, Journal of Immunology, 181, 6923 - 6933, 2008年11月
- Dendritic cells are specialized accessory cells along with TGF-β for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3- precursors, Sayuri Yamazaki, Sayuri Yamazaki, Anthony J. Bonito, Radek Spisek, Madhav Dhodapkar, Kayo Inaba, Ralph M. Steinman, Blood, 110, 4293 - 4302, 2007年12月
- Production of monoclonal antibodies that recognize the extracellular domain of mouse Langerin/CD207, Cheolho Cheong, Juliana Idoyaga, Yoonkyung Do, Maggi Pack, Sung Ho Park, Haekyung Lee, Young Sun Kang, Young Sun Kang, Jae Hoon Choi, Jae Y. Kim, Anthony Bonito, Kayo Inaba, Sayuri Yamazaki, Ralph M. Steinman, Chae Gyu Park, Journal of Immunological Methods, 324, 48 - 62, 2007年07月
- Differential antigen processing by dendritic cell subsets in vivo, Diana Dudziak, Alice O. Kamphorst, Gordon F. Heidkamp, Veit R. Buchholz, Christine Trumpfheller, Sayuri Yamazaki, Cheolho Cheong, Kang Liu, Han Woong Lee, Gyu Park Chae, Ralph M. Steinman, Michel C. Nussenzweig, Michel C. Nussenzweig, Science, 315, 107 - 111, 2007年01月
- Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+T cell immunity to mouse survivin, Anna Charalambous, Margarita Oks, Godwin Nchinda, Sayuri Yamazaki, Ralph M. Steinman, Ralph M. Steinman, Journal of Immunology, 177, 8410 - 8421, 2006年12月
- Dendritic cells expand antigen-specific Foxp3+CD25 +CD4+ regulatory T cells including suppressors of alloreactivity, Sayuri Yamazaki, Sayuri Yamazaki, Kayo Inaba, Kristin V. Tarbell, Ralph M. Steinman, Immunological Reviews, 212, 314 - 329, 2006年08月
- CD4+CD25+Foxp3+T cells and CD4+CD25-Foxp3+T cells in aged mice, Tomohisa Nishioka, Jun Shimizu, Jun Shimizu, Ryuji Iida, Sayuri Yamazaki, Shimon Sakaguchi, Shimon Sakaguchi, Journal of Immunology, 176, 6586 - 6593, 2006年06月
- The interactions of dendritic cells with antigen-specific, regulatory T cells that suppress autoimmunity, Kristin V. Tarbell, Sayuri Yamazaki, Ralph M. Steinman, Seminars in Immunology, 18, 93 - 102, 2006年04月
- Effective expansion of alloantigen-specific Foxp3+ CD25 + CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction, Sayuri Yamazaki, Munjal Patel, Alice Harper, Anthony Bonito, Hidehiro Fukuyama, Maggi Pack, Kristin V. Tarbell, Mia Talmor, Jeffrey V. Ravetch, Kayo Inaba, Ralph M. Steinman, Proceedings of the National Academy of Sciences of the United States of America, 103, 2758 - 2763, 2006年02月
- The innate functions of dendritic cells in peripheral lymphoid tissues, Ralph M. Steinman, Laura Bonifaz, Shin Ichiro Fujii, Kang Liu, David Bonnyay, Sayuri Yamazaki, Maggi Pack, Daniel Hawiger, Tomonori Iyoda, Kayo Inaba, Michel C. Nussenzweig, Advances in Experimental Medicine and Biology, 560, 83 - 97, 2005年12月01日
- Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells, Kuibeom Ko, Kuibeom Ko, Sayuri Yamazaki, Kyoko Nakamura, Tomohisa Nishioka, Keiji Hirota, Tomoyuki Yamaguchi, Jun Shimizu, Takashi Nomura, Tsutomu Chiba, Shimon Sakaguchi, Shimon Sakaguchi, Journal of Experimental Medicine, 202, 885 - 891, 2005年10月
- Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells, Haruhiko Yagi, Haruhiko Yagi, Takashi Nomura, Kyoko Nakamura, Sayuri Yamazaki, Toshio Kitawaki, Shohei Hori, Michiyuki Maeda, Masafumi Onodera, Takashi Uchiyama, Shingo Fujii, Shimon Sakaguchi, Shimon Sakaguchi, Shimon Sakaguchi, International Immunology, 16, 1643 - 4656, 2004年11月
- CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes, Kristin V. Tarbell, Sayuri Yamazaki, Kara Olson, Priscilla Toy, Ralph M. Steinman, Ralph M. Steinman, Journal of Experimental Medicine, 199, 1467 - 1477, 2004年06月
- Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice, Noriko Sakaguchi, Noriko Sakaguchi, Takeshi Takahashi, Hiroshi Hata, Takashi Nomura, Tomoyuki Tagami, Sayuri Yamazaki, Toshiko Sakihama, Takaji Matsutani, Izumi Negishi, Syuichi Nakatsuru, Shimon Sakaguchi, Shimon Sakaguchi, Nature, 426, 454 - 460, 2003年11月
- Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells, Sayuri Yamazaki, Tomonori Iyoda, Kristin Tarbell, Kara Olson, Klara Velinzon, Kayo Inaba, Ralph M. Steinman, Ralph M. Steinman, Journal of Experimental Medicine, 198, 235 - 247, 2003年07月
- SIGN-R1, a novel C-type lectin expressed by marginal zone macrophages in spleen, mediates uptake of the polysaccharide dextran, Young Sun Kang, Sayuri Yamazaki, Tomonori Iyoda, Maggie Pack, Sandra A. Bruening, Jae Y. Kim, Kazuhiko Takahara, Kayo Inaba, Ralph M. Steinman, Chae Gyu Park, International Immunology, 15, 177 - 186, 2003年02月
- Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance, Jun Shimizu, Sayuri Yamazaki, Takeshi Takahashi, Yasumasa Ishida, Shimon Sakaguchi, Nature Immunology, 3, 135 - 142, 2002年01月
- Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance, Shimon Sakaguchi, Shimon Sakaguchi, Noriko Sakaguchi, Jun Shimizu, Sayuri Yamazaki, Toshiko Sakihama, Misako Itoh, Yuhshi Kuniyasu, Takashi Nomura, Masaaki Toda, Takeshi Takahashi, Immunological Reviews, 182, 18 - 32, 2001年11月
- Immunologic self tolerance maintained by T-cell-mediated control of self-reactive T cells: Implications for autoimmunity and tumor immunity, Shimon Sakaguchi, Takeshi Takahashi, Sayuri Yamazaki, Yuhshi Kuniyasu, Misako Itoh, Noriko Sakaguchi, Jun Shimizu, Microbes and Infection, 3, 911 - 918, 2001年01月
- Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4, Takeshi Takahashi, Tomoyuki Tagami, Sayuri Yamazaki, Toshimitsu Uede, Jun Shimizu, Noriko Sakaguchi, Tak W. Mak, Shimon Sakaguchi, Shimon Sakaguchi, Journal of Experimental Medicine, 192, 303 - 309, 2000年07月
- Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity, Jun Shimizu, Sayuri Yamazaki, Shimon Sakaguchi, Shimon Sakaguchi, Shimon Sakaguchi, Journal of Immunology, 163, 5211 - 5218, 1999年11月
- Treatment of reticular erythematous mucinosis with a large dose of ultraviolet B radiation and steroid impregnated tape, Sayuri Yamazaki, Ichiro Katayama, Yuko Kurumaji, Hiroo Yokozeki, Kiyoshi Nishioka, Journal of Dermatology, 26, 115 - 118, 1999年01月
- A case of pediatric Behcet's disease with intestinal involvement, Sayuri Yamazaki, Sayuri Yamazaki, Sayuri Yamazaki, Taeko Koyano, Journal of Dermatology, 26, 160 - 163, 1999年01月
- Childhood bullous pemphigoid associated with chronic renal allograft rejection [4], S. Yamazaki, H. Yokozeki, L. Katayama, R. Komai, T. Hashimoto, K. Nishiok, British Journal of Dermatology, 138, 547 - 548, 1998年04月14日
- TNF-α, RANTES, and MCP-1 are major chemoattractants of murine Langerhans cells to the regional lymph nodes, S. Yamazaki, H. Yokozeki, T. Satoh, I. Katayama, K. Nishioka, Experimental Dermatology, 7, 35 - 41, 1998年01月
- Production of chemotactic factor(s) of Langerhans cells by lymph node cells in contact sensitivity, Sayuri Yamazaki, Ichiro Katayama, Hiroo Yokozeki, Takahiro Satoh, Kiyoshi Nishioka, Journal of Dermatological Science, 11, 51 - 58, 1996年01月
- Contact urticaria induced by mexiletine hydrochloride in a patient receiving iontophoresis, S. Yamazaki, I. Katayama, Y. Kurumaji, H. Yokozeki, K. Nishioka, British Journal of Dermatology, 130, 538 - 540, 1994年01月01日
- Acral ichthyosiform mucinosis in association with Sjogren's syndrome: A peculiar form of pretibial myxedema?, S. Yamazaki, I. Katayama, T. Satoh, H. Yokozeki, K. Nishioka, Journal of Dermatology, 20, 715 - 718, 1993年01月
- Reproductive tract tumours in Peutz-Jeghers syndrome [4], S. Yamazaki, I. Katayama, H. Yokozeki, K. Nishioka, British Journal of Dermatology, 128, 466 - 467, 1993年01月01日
- Giant mucocele of oral cavity as a mucocutaneous manifestation of Sjogren syndrome, I. Katayama, S. Yamazaki, K. Nishioka, Journal of Dermatology, 20, 238 - 241, 1993年01月
- Mechanisms of desensitization in delayed cutaneous hypersensitivity. Modulation of T-cell response by haptenized amino acid, I. Katayama, T. Sato, S. Yamazaki, H. Yokozeki, K. Nishioka, Journal of Dermatology, 19, 741 - 743, 1992年01月01日