T Kanno; T Katano; T Shimura; R Nishigaki; Y Kojima; M Sasaki; Y Okuda; N Sugimura; S Fukusada; Y Mizuno; H Iwasaki; H Nishie; M Tanaka; K Ozeki; E Kubota; S Tanida; H Kataoka
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 54 (7) 905 - 910 2021/12
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 51 (7) 967 - 971 1590-8658 2019/07 [Refereed]
大腸鋸歯状病変における、遺伝子変異、コピー数変化、DNAメチル化の統合解析(Integrative analysis of gene mutations, copy number alterations and DNA methylation in colorectal serrated lesions)
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 22 (3) 295 - 300 1744-9979 2018/06 [Refereed]
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 44 (11) 940 - 4 2012/11 [Refereed]
Krishna P. Sarker; Hiromi Kataoka; Angela Chan; Stuart J. Netherton; Isabelle Pot; Mai Anh Huynh; Xiaolan Feng; Azad Bonni; Karl Riabowol; Shirin Bonni
T Wada; M Sasaki; H Kataoka; S Tanida; K Itoh; N Ogasawara; T Oshima; S Togawa; E Kubota; T Yamada; Y Mori; F Fujita; H Ohara; H Nakao; S Sobue; T Joh; M Itoh
T. Wada; M. Sasaki; H. Kataoka; S. Tanida; K. Itoh; N. Ogasawara; T. Oshima; S. Togawa; E. Kubota; T. Yamada; Y. Mori; F. Fujita; H. Ohara; H. Nakao; S. Sobue; T. Joh; M. Itoh
M. Sasaki; K. Imaeda; N. Okayama; T. Mizuno; H. Kataoka; T. Kamiya; E. Kubota; N. Ogasawara; Y. Funaki; M. Mizuno; A. Iida; C. Goto; S. Koikeda; K. Kasugai; T. Joh Diabetes, Obesity and Metabolism 14- 379 -382 2012/04
臨床標本及びヒト化肝臓をもつマウスを用いた肝細胞癌における後成的変化の解析(Analysis of epigenetic alterations in hepatocellular carcinoma using clinical samples and mice with humanized liver)
Y. Hirata; N. Ogasawara; M. Sasaki; T. Mizushima; T. Shimura; T. Mizoshita; Y. Mori; E. Kubota; T. Wada; S. Tanida; H. Kataoka; T. Kamiya; S. Higashiyama; T. Joh British Journal of Cancer 100- 1320 -1329 2009/04
Takaya Shimura; Takaya Shimura; T. Joh; M. Sasaki; H. Kataoka; S. Tanida; N. Ogasawara; T. Yamada; E. Kubota; T. Wada; M. Inukai; N. Yoshioka; Y. Saida Acta Gastro-Enterologica Belgica 70- 323 -330 2007/10
T Oshima; T Joh; F Fujita; Y Mori; T Yamada; E Kubota; T Wada; S Togawa; N Ogasawara; K Itoh; S Tanida; H Kataoka; M Sasaki; M Itoh GASTROENTEROLOGY 128- (4) A599 -A599 2005/04
T Wada; T Joh; F Fujita; Y Mori; E Kubota; S Togawa; N Ogasawara; T Oshima; K Ito; T Yamada; S Tanida; H Kataoka; M Sasaki; M Ito GASTROINTESTINAL ENDOSCOPY 61- (5) AB96 -AB96 2005/04
M Mizuno; N Okayama; K Kasugai; T Yoshida; M Miyata; M Nitta; H Kataoka; S Akita; T Joh; M Itoh; K Asai; T Kato GASTROENTEROLOGY 118- (4) A1277 -A1277 2000/04
Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Date (from‐to) : 2018/04 -2021/03
Author : Hayashi Noriyuki
Elucidation of mechanisms underlying angiogenesis is important for the development of new anti-angiogenic drugs. Here, we found that EIF3D, a critical translational factor, is ubiquitinated by the cullin-3 (CUL3)/KCTD10 ubiquitin ligase complex in both endothelial cells and hepatocellular carcinoma cells. Knockdown of EIF3D in endothelial cells drastically inhibited tube formation of endothelial cells, that mimics angiogenesis in vitro. Our results suggest that CUL3/KCTD10/EIF3D would be a promising target for development of novel anti-angiogenic drugs.
腫瘍溶解性ウイルスによる抗がん免疫応答の解析と新規消化管がん治療開発への応用
Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)