Researchers Database
YAMANAKA TomoyasuGraduate School of Medical Sciences Department of Neurosurgery Assistant Professor | |||
Last Updated :2025/09/30
Published Papers
- Tomoyasu Yamanaka; Yusuke Nishikawa; Takashi Iwata; Teishiki Shibata; Mitsuru Uchida; Yuki Hayashi; Hiroyuki Katano; Motoki Tanikawa; Shigeki Yamada; Mitsuhito MaseFluids and Barriers of the CNS Springer Science and Business Media LLC 20 (1) 2023/12 [Refereed]
MISC
- 山中 智康; 片野 広之; 谷川 元紀; 岡 雄一; 坂田 知宏; 西川 祐介; 山田 紘史; 内田 充; 林 裕樹; 藤浪 亮太; 山田 茂樹 日本脳神経外傷学会プログラム・抄録集 46回- 153 -153 2023/02
Research Grants & Projects
- 日本学術振興会：科学研究費助成事業Date (from‐to) : 2022/04 -2025/03Author : 山田 紘史; 山中 智康; 間瀬 光人; 菅 博人
- Japan Society for the Promotion of Science：Grants-in-Aid for Scientific ResearchDate (from‐to) : 2018/04 -2024/03Author : Mase MitsuhitoLipokalin-type Prostaglandin D synthase (L-PGDS) is known to be a carrier protein in cerebrospinal fluid (CSF), which scavenges biliverdin (metabolites of hemoglobin) in patients with subarachnoid hemorrhage (SAH). The purpose of this study is to clarify the drainage route of the system from CSF to extracranial regions in mice and human by using L-PGDS as an internal tracer. However, it is very difficult to make mice SAH model because of high mortality. It is a pity that we have not obtained enough experimental data. The study is on-going. We also analyzed H215O dynamic PET in human to clarify water turnover in brain and CSF. The second study showed very fast movement of water molecules from artery to brain parenchyma and CSF. Interestingly, water in basal cisterns was faster than cortical subarachnoid space or ventricles, suggesting that brain stem may have a unique role for water supply into CSF.