Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research
Date (from‐to) : 2012/04 -2015/03
Author : TAKAHASHI SHUJI; ARIIZUMI Takashi; TANAKA Toshiaki; NINOMIYA Hiromasa
In this study, we screened switch factors for two different endoderm in Xenopus. Using information from DNA array and study of the other model animals, a lot of gene are cloned and tested by overexpression.
However, the factors did not identified. We are trying to functional screening.
We developed a new induction method from human iPS cell to embryonic endoderm. Using this methods, We are trying to induce pancreatic endoderm.