Researcher Database


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HOSODA Nao

FacultyGraduate School of Pharmaceutical Sciences Department of Biological Chemistry
PositionAssociate Professor
Mail
HomepageURLhttp://www.phar.nagoya-cu.ac.jp/resarch_course/res_course12.html
Birthday
Last Updated :2020/07/02

Researcher Profile and Settings

Education

  •  - 1997 , The University of Tokyo

Degree

  • 東京大学薬学系研究科/博士(薬学)

Academic & Professional Experience

  •   2011 04  - 現在, Nagoya City University, Graduate School of Pharmaceutical Sciences
  •   2007 04  - 2011 03 , Nagoya City University, Graduate School of Pharmaceutical Sciences
  •   2006 06  - 2007 03 , Nagoya City University, Graduate School of Pharmaceutical Sciences
  •   2002 04  - 2004 07 , The University of Tokyo, Graduate School of Medicine

Research Activities

Published Papers

  • A novel method for stabilizing microRNA mimics., Nogimori T, Furutachi K, Ogami K, Hosoda N, Hoshino SI, Biochemical and biophysical research communications, 511, (2) 422 - 426, 04 , Refereed
  • TDP-43 accelerates deadenylation of target mRNAs by recruiting Caf1 deadenylase., Fukushima M, Hosoda N, Chifu K, Hoshino SI, FEBS letters, 593, (3) 277 - 287, 12 , Refereed
  • Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway., Nogimori T, Nishiura K, Kawashima S, Nagai T, Oishi Y, Hosoda N, Imataka H, Kitamura Y, Kitade Y, Hoshino SI, Nucleic acids research, 47, (1) 432 - 449, 11 , Refereed
  • Proteolysis: a double-edged sword for the development of amyloidoses., Okamoto A, Hosoda N, Hoshino SI, Prion, 1 - 7, 09 , Refereed
  • Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail., Sawazaki R, Imai S, Yokogawa M, Hosoda N, Hoshino SI, Mio M, Mio K, Shimada I, Osawa M, Scientific reports, 8, (1) , 01 , Refereed
  • The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells., Saito S, Hosoda N, Hoshino S, The Journal of biological chemistry, 288, (24) 17832 - 17843, 06 , Refereed
  • Failsafe nonsense-mediated decay does not detectably target eIF4E-bound mRNA., Matsuda D, Hosoda N, Kim YK, Maquat LE, Nature structural & molecular biology, 14, 974-979, (10) 974 - 979, 10 , Refereed
  • [Features of NMD (nonsense-mediated mRNA decay) in mammalian cells]., Hosoda N, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 51, (16 Suppl) 2544 - 2548, 12 , Refereed
  • CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells., Hosoda N, Kim YK, Lejeune F, Maquat LE, Nature structural & molecular biology, 12/,893-901, (10) 893 - 901, 10 , Refereed
  • Enzymaic and signal transduction properties of CD38/NADase and PC-1/ phosphodiesterase., Chem. Immunol., 75/,60-78
  • Novel function of the Eukaryotic Polypeptide-chain Releasing Factor 3 (eRF3/GSPT) in the Mechanism of mRNA Degradation., Biochemistry, 64/,1367-1372
  • Inhibition of phosphodiesterase/pyrophosphatase activity of PC-1 by its association with glycosaminoglycans., 265/,763-770
  • Protein-tyrosine phosphorylation by IgG1 subclass CD38 monoclonal antibodies is mediated through stimulation of the FcgII receptors in human myeloid cell lines., J. Immunol., 159/,5226-5232

Misc

  • 躍進するRNA研究 進展する構造解析,機能性RNAの多彩な役割の解明とRNAiなど生命・医工学への応用 第2章 RNAによる遺伝子発現調節 3)翻訳調節とmRNA動態 2.ウイルスRNA翻訳制御, 細田直, 野本明男, 実験医学, 22, (17) 2469 - 2474,   2004 11 25

Patents

  • 特願2016-219227, 特開2018-074954
  • 特願2014-263857, 特開2015-226531
  • 特願2014-107562, 特開2015-221026


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