伊藤　圭馬 (イトウ　ケイマ)

研究者情報

学位

• 博士(医学)（2024年03月 名古屋市立大学）

科研費研究者番号

• 51000921

ORCID ID

•  https://orcid.org/0000-0002-9217-6956

J-Global ID

• 202301018427950659

研究キーワード

• 喘息   慢性咳嗽   機能性消化管疾患   

研究分野

• ライフサイエンス / 呼吸器内科学

学歴

• 2019年04月 - 2024年03月   名古屋市立大学大学院   医学研究科   博士課程
• 2009年04月 - 2015年03月   名古屋市立大学   医学部   医学科

所属学協会

• 日本咳嗽学会   日本喘息学会   日本アレルギー学会   日本呼吸器内視鏡学会   日本呼吸器学会   日本内科学会   

研究活動情報

論文

• Risk Factors for Liver Injury and Their Association with Treatment in Hospitalized Patients with COVID-19.

  Chihiro Kato; Yutaka Ito; Yuta Mori; Keima Ito; Kensuke Fukumitsu; Satoshi Fukuda; Yoshihiro Kanemitsu; Takehiro Uemura; Tomoko Tajiri; Hirotsugu Ohkubo; Tetsuya Oguri; Atsushi Nakamura; Akio Niimi

  Internal medicine (Tokyo, Japan) 2025年03月
• Staphylococcus aureus enterotoxin sensitization is associated with declined capsaicin cough sensitivity in chronic obstructive pulmonary disease.

  Yoshihiro Kanemitsu; Kensuke Fukumitsu; Ryota Kurokawa; Taisuke Akamatsu; Satoshi Fukuda; Yutaka Ito; Yuki Amakusa; Tatsuro Suzuki; Keima Ito; Yuta Mori; Takehiro Uemura; Tomoko Tajiri; Hirotsugu Ohkubo; Toshihiro Shirai; Akio Niimi

  Scientific reports 14 1 29613 - 29613 2024年11月
• Productive cough associated with patient-reported outcomes and computed tomography analysis results in idiopathic pulmonary fibrosis: a single centre cross-sectional study.

  Kohei Fujita; Yoshihiro Kanemitsu; Hirotsugu Ohkubo; Akihito Okada; Akiko Nakano; Keima Ito; Yuta Mori; Kensuke Fukumitsu; Satoshi Fukuda; Takehiro Uemura; Tomoko Tajiri; Yutaka Ito; Tetsuya Oguri; Yoshiyuki Ozawa; Takayuki Murase; Akio Niimi

  ERJ open research 10 5 2024年09月
• Usefulness of serum transthyretin for prediction of the 1-year outcome in idiopathic pulmonary fibrosis: An evaluation of sarcopenic and nutritional indicators.

  Kohei Fujita; Akihito Okada; Hirotsugu Ohkubo; Akiko Nakano; Keima Ito; Yuta Mori; Kensuke Fukumitsu; Satoshi Fukuda; Yoshihiro Kanemitsu; Takehiro Uemura; Tomoko Tajiri; Yutaka Ito; Tetsuya Oguri; Yoshiyuki Ozawa; Takayuki Murase; Akio Niimi

  Respiratory investigation 62 5 889 - 896 2024年08月
• Prevalence and clinical relevance of comorbid pertussis infection in adult patients with asthma: A prospective, cross-sectional study.

  Hirono Nishiyama; Tomoko Tajiri; Ryota Kurokawa; Tatsuro Suzuki; Keima Ito; Yuta Mori; Kensuke Fukumitsu; Satoshi Fukuda; Yoshihiro Kanemitsu; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Respiratory investigation 62 5 811 - 816 2024年07月
• Efficacy of dupilumab for severe chronic rhinosinusitis with nasal polyps and asthma: A prospective study.

  Tomoko Tajiri; Motohiko Suzuki; Hirono Nishiyama; Yoshiyuki Ozawa; Ryota Kurokawa; Keima Ito; Kensuke Fukumitsu; Yuta Mori; Yoshihiro Kanemitsu; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Shinichi Iwasaki; Akio Niimi

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2024年07月
• Comorbid functional dyspepsia reflects IL-33-mediated airway neuronal dysfunction in asthma.

  Keima Ito; Yoshihiro Kanemitsu; Takashi Ueda; Takeshi Kamiya; Eiji Kubota; Yuta Mori; Kensuke Fukumitsu; Tomoko Tajiri; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Yutaka Ito; Yasuhiro Shibata; Natsuko Kumamoto; Shinya Ugawa; Akio Niimi

  The Journal of allergy and clinical immunology 2024年06月
• Efficacy of dupilumab for airway hypersecretion and airway wall thickening in patients with moderate-to-severe asthma: A prospective, observational study

  Tomoko Tajiri; Motohiko Suzuki; Hirono Nishiyama; Yoshiyuki Ozawa; Ryota Kurokawa; Norihisa Takeda; Keima Ito; Kensuke Fukumitsu; Yoshihiro Kanemitsu; Yuta Mori; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Kenji Izuhara; Akio Niimi

  Allergology International 2024年03月
• Low Daily Step Count Associated with Small Erector Spine Muscle Area and Sarcopenia in Idiopathic Pulmonary Fibrosis.

  Hirotsugu Ohkubo; Kohei Fujita; Keima Ito; Akiko Nakano; Minoru Horiuchi; Yuta Mori; Kensuke Fukumitsu; Satoshi Fukuda; Yoshihiro Kanemitsu; Takehiro Uemura; Tomoko Tajiri; Yutaka Ito; Yoshiyuki Ozawa; Takayuki Murase; Akio Niimi

  Internal medicine (Tokyo, Japan) 2023年10月
• Bronchial thermoplasty improves cough hypersensitivity and cough in severe asthmatics.

  Hirono Nishiyama; Yoshihiro Kanemitsu; Johsuke Hara; Kensuke Fukumitsu; Norihisa Takeda; Ryota Kurokawa; Keima Ito; Tomoko Tajiri; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Respiratory medicine 216 107303 - 107303 2023年09月
• Targeting the interleukin-5 pathway improves cough hypersensitivity in patients with severe uncontrolled asthma

  Keima Ito; Yoshihiro Kanemitsu; Kensuke Fukumitsu; Tomoko Tajiri; Hirono Nishiyama; Yuta Mori; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Annals of Allergy, Asthma & Immunology 131 2 203 - 208.e1 2023年08月
• Tiotropium for refractory cough in asthma via cough reflex sensitivity: A randomized, parallel, open-label trial

  Kensuke Fukumitsu; Yoshihiro Kanemitsu; Ryota Kurokawa; Norihisa Takeda; Tomoko Tajiri; Hirono Nishiyama; Keima Ito; Yoshitsugu Inoue; Sayaka Yamamoto; Yuta Mori; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Annals of Allergy, Asthma & Immunology 131 1 59 - 68.e3 2023年07月
• Functional gastrointestinal disorders are associated with capsaicin cough sensitivity in severe asthma

  Keima Ito; Yoshihiro Kanemitsu; Takeshi Kamiya; Kensuke Fukumitsu; Norihisa Takeda; Tomoko Tajiri; Ryota Kurokawa; Hirono Nishiyama; Jennifer Yap; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Allergology International 72 2 271 - 278 2023年04月
• Decreased capsaicin cough reflex sensitivity predicts hospitalisation due to COPD.

  Yoshihiro Kanemitsu; Ryota Kurokawa; Taisuke Akamatsu; Kensuke Fukumitsu; Satoshi Fukuda; Yutaka Ito; Norihisa Takeda; Hirono Nishiyama; Keima Ito; Tomoko Tajiri; Yuta Mori; Takehiro Uemura; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Tetsuya Oguri; Toshihiro Shirai; Akio Niimi

  BMJ open respiratory research 10 1 2023年01月
• Specific IgE Response and Omalizumab Responsiveness in Severe Allergic Asthma.

  Tomoko Tajiri; Motohiko Suzuki; Takeo Kutsuna; Hirono Nishiyama; Keima Ito; Norihisa Takeda; Kensuke Fukumitsu; Yoshihiro Kanemitsu; Satoshi Fukuda; Takehiro Umemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Kosho Yoshikawa; Akio Niimi

  Journal of asthma and allergy 16 149 - 157 2023年
• Residual Dyspnea May Predict Small Airways Dysfunction and Poor Responsiveness to Single-Inhaler Triple Therapy in Asthmatic Patients

  Keima Ito; Tomoko Tajiri; Hirono Nishiyama; Ryota Kurokawa; Jenifer Maries Go Yap; Norihisa Takeda; Kensuke Fukumitsu; Yoshihiro Kanemitsu; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Journal of Asthma and Allergy 2022年11月
• Characteristics of the European Thoracic Society/American Thoracic Society severe asthma definition as a determinant of future use of biologics/bronchial thermoplasty.

  Hirono Nishiyama; Yoshihiro Kanemitsu; Kensuke Fukumitsu; Norihisa Takeda; Ryota Kurokawa; Tomoko Tajiri; Keima Ito; Jenifer Maries Go Yap; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Asia Pacific allergy 12 2 e13  2022年04月
• Reflux-related symptoms reflect poor asthma control and the presence of airway neuronal dysfunction.

  Ryota Kurokawa; Yoshihiro Kanemitsu; Kensuke Fukumitsu; Norihisa Takeda; Tomoko Tajiri; Hirono Nishiyama; Jennifer Maries Yap; Keima Ito; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Masaya Takemura; Akio Niimi

  Allergology international : official journal of the Japanese Society of Allergology 71 3 318 - 324 2022年01月
• Pretreatment Alveolar Nitric Oxide Levels Predict Improvement of Pulmonary Function 1 Year Following Anti-Asthma Treatments in Patients with Inhaled Corticosteroid-Naïve Asthma.

  Kensuke Fukumitsu; Hirono Nishiyama; Yoshihiro Kanemitsu; Norihisa Takeda; Ryota Kurokawa; Tomoko Tajiri; Keima Ito; Jenifer Maries Go Yap; Sayaka Yamamoto; Yoshitsugu Inoue; Satoshi Fukuda; Takehiro Uemura; Osamu Takakuwa; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Motohiko Suzuki; Masaya Takemura; Akio Niimi

  International archives of allergy and immunology 183 5 479 - 489 2022年
• COVID‐19 pneumonia suspected to be co‐infection with Mycoplasma pneumoniae and improved by early administration of favipiravir and ciclesonide

  Keima Ito; Takako Yokoyama; Minoru Horiuchi; Munehiro Kato; Ikuji Usami

  Respirology Case Reports 2021年09月
• The impact of budesonide inhalation suspension for asthma hospitalization: In terms of length of stay, recovery time from symptoms, and hospitalization costs

  Keima Ito; Yoshihiro Kanemitsu; Kensuke Fukumitsu; Yoshitsugu Inoue; Hirono Nishiyama; Sayaka Yamamoto; Yuki Kitamura; Ryota Kurokawa; Norihisa Takeda; Satoshi Fukuda; Takehiro Uemura; Tomoko Tajiri; Osamu Takakuwa; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Akio Niimi

  Allergology International 69 4 571 - 577 2020年10月
• A case of non-small cell lung cancer with long-term response after re-challenge with nivolumab

  Keima Ito; Tetsuya Oguri; Norihisa Takeda; Kensuke Fukumitsu; Satoshi Fukuda; Yoshihiro Kanemitsu; Tomoko Tajiri; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Akio Niimi

  Respiratory Medicine Case Reports 29 100979 - 100979 2020年
• Aortoesophageal Fistula Occurring during Lung Cancer Treatment: A Case Treated by Thoracic Endovascular Aortic Repair

  Keima Ito; Tetsuya Oguri; Akiko Nakano; Kensuke Fukumitsu; Satoshi Fukuda; Yoshihiro Kanemitsu; Osamu Takakuwa; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Akio Niimi

  Internal Medicine 58 20 3025 - 3028 2019年10月
• Small airway inflammation is associated with residual airway hyperresponsiveness in Th2-high asthma

  Takamitsu Asano; Yoshihiro Kanemitsu; Masaya Takemura; Kensuke Fukumitsu; Ryota Kurokawa; Yoshitsugu Inoue; Norihisa Takeda; Jennifer Maries G. Yap; Keima Ito; Yuki Kitamura; Satoshi Fukuda; Hirotsugu Ohkubo; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Akio Niimi

  Journal of Asthma 57 9 933 - 941 2019年06月
• A suspected case of inflammatory bronchial polyp induced by bronchial thermoplasty but resolved spontaneously

  Akira Takeuchi; Yoshihiro Kanemitsu; Osamu Takakuwa; Keima Ito; Yuki Kitamura; Yoshitsugu Inoue; Norihisa Takeda; Kensuke Fukumitsu; Takamitsu Asano; Satoshi Fukuda; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Tetsuya Oguri; Akio Niimi

  Journal of Thoracic Disease 10 9 E678 - E681 2018年09月
• Predictive and Prognostic Value of CYFRA 21-1 for Advanced Non-small Cell Lung Cancer Treated with EGFR-TKIs

  Akira Takeuchi; Tetsuya Oguri; Kazuki Sone; Keima Ito; Yuki Kitamura; Yoshitsugu Inoue; Takamitsu Asano; Satoshi Fukuda; Yoshihiro Kanemitsu; Osamu Takakuwa; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Akio Niimi

  Anticancer Research 37 10 2017年10月
• Predictive Role of CYFRA21-1 and CEA for Subsequent Docetaxel in Non-small Cell Lung Cancer Patients

  Kazuki Sone; Tetsuya Oguri; Keima Ito; Yuki Kitamura; Yoshitsugu Inoue; Akira Takeuchi; Satoshi Fukuda; Osamu Takakuwa; Ken Maeno; Takamitsu Asano; Yoshihiro Kanemitsu; Hirotsugu Ohkubo; Masaya Takemura; Yutaka Ito; Akio Niimi

  Anticancer Research 37 9 2017年09月

講演・口頭発表等

• The Impact of Treatable Traits on Antitussive Rate in Chronic Cough

  Keima Ito; Yoshihiro Kanemitsu; Yuki Amakusa; Tatsuro Suzuki; Yuta Mori; Kensuke Fukumitsu; Satoshi Fukuda; Takehiro Uemura; Tomoko Tajiri; Yutaka Ito; Akio Niimi

  American Thoracic Society 2025 International Conference 2025年05月
• Functional Dyspepsia Is a Comorbidity Reflecting IL-33-mediated Airway Neuronal Dysfunction in Asthma

  Keima Ito, Yoshihiro Kanemitsu, Takashi Ueda, Takeshi Kamiya, Eiji Kubota, Yuta Mori, Kensuke Fukumitsu, Tomoko Tajiri, Shinya Ugawa, Akio Niimi

  American Thoracic Society 2024 International Conference 2024年05月 口頭発表（一般）
• Targeting the IL-5 pathway improves cough hypersensitivity in patients with severe uncontrolled asthma

  Keima Ito; Yoshihiro Kanemitsu; Tatsuro Suzuki; Yuta Mori; Kensuke Fukumitsu; Satoshi Fukuda; Takehiro Uemura; Tomoko Tajiri; Yutaka Ito; Akio Niimi

  British Thracic Society Winter Meeting 2023 2023年11月 口頭発表（一般）
• Residual dyspnea may predict small airways dysfunction and poor responsiveness to single-inhaler triple therapy in asthmatic patients

  Keima Ito; Tomoko Tajiri; Tatsuro Suzuki; Yuta Mori; Kensuke Fukumitsu; Satoshi Fukuda; Yoshihiro Kanemitsu; Takehiro Uemura; Masaya Takemura; Yutaka Ito; Tetsuya Oguri; Akio Niimi

  American Thoracic Society 2023 International Conference 2023年05月 ポスター発表
• Functional gastrointestinal disorders affect capsaicin cough reflex sensitivity in severe asthma

  Keima Ito; Yoshihiro Kanemitsu; Akio Niimi

  International Collaborative Asthma Network Young Researchers Forum 2022年05月 口頭発表（一般）
• Retrospective study of the current status and short-term effectiveness of single-inhaler triple therapy for asthma or asthma and COPD overlap

  Keima Ito; Tomoko Tajiri; Hirono Nishiyama; Ryota Kurokawa; Norihisa Takeda; Kensuke Fukumitsu; Yoshihiro Kanemitsu; Satoshi Fukuda; Takehiro Uemura; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Akio Niimi

  The 25th Congress of the Asian Pacific Society of Respirology 2021年11月 ポスター発表
• Procaterol / Budesonide combined nebulizer inhalation therapy shortens hospitalization for asthma attacks

  Keima Ito; Yoshihiro Kanemitsu; Yoshitsugu Inoue; Sayaka Yamamoto; Hirono Nishiyama; Ryota Kurokawa; Norihisa Takeda; Kensuke Fukumitsu; Satoshi Fukuda; Hirotsugu Ohkubo; Masaya Takemura; Ken Maeno; Yutaka Ito; Akio Niimi

  American Thoracic Society 2019 International Conference 2019年05月 ポスター発表

MISC

• 喘息と機能性ディスペプシアにおけるIL-33を介する気道の神経機能不全の関連性

  伊藤圭馬; 金光禎寛 臨床免疫・アレルギー科 83 (3) 283 -291 2025年03月
• 嚥下性肺炎を契機に診断に至った筋萎縮性側索硬化症の1例

  伊藤圭馬; 小林玄弥; 川口裕子; 竹山慎二 総合診療 29 (6) 2019年

受賞

• 2024年09月 日本咳嗽学会 第26回日本咳嗽学会学術大会 最優秀演題賞
  
• 2022年04月 日本アレルギー学会 第18回日本アレルギー学会学術大会賞
  

共同研究・競争的資金等の研究課題

• 喘息病態のバイオマーカーとしての血清胆汁酸の意義

  日本学術振興会：科学研究費助成事業

  研究期間 : 2025年04月 -2028年03月 

  代表者 : 伊藤 圭馬
• 喘息病態における気道神経機能不全の発症メカニズムの解明と治療戦略の探索

  日本学術振興会：科学研究費助成事業

  研究期間 : 2024年07月 -2026年03月 

  代表者 : 伊藤 圭馬
• 知覚神経機能不全に着目した、喘息と機能性ディスペプシアの病態連関の検討

  日本呼吸器学会：喘息研究支援プログラムB

  研究期間 : 2023年12月 -2024年11月 

  代表者 : 伊藤 圭馬

その他のリンク

researchmap

https://researchmap.jp/48691116