研究者データベース

今泉 祐治 (イマイズミ ユウジ)

  • 学長・副学長等 特任教授
Last Updated :2020/08/07

研究者情報

学位

  • 東京大学薬学系研究科生命薬学/博士(薬学)

J-Global ID

プロフィール

  • 1976年3月 東京大学 薬学部 卒業

    1978年3月 東京大学 薬学系大学院 修士課程 修了

    1978年4月 名古屋市立大学 薬学部 薬品作用学講座 助手

    1981年12月 薬学博士(東京大学)

    1982年12月 名古屋市立大学 薬学部 薬品作用学講座 助教授

    1985年6月 カルガリー大学 医学部 生理学講座 長期海外出張(~1987年6月)

    1992年3月 日本薬理学会学術奨励賞受賞「各種平滑筋細胞の興奮性の多様性とその機序について」

    1997年1月 名古屋市立大学 薬学部 薬物治療学講座 教授

    2000年4月 名古屋市立大学 薬学部 薬品作用学講座 教授(担当替え)

    2002年4月 名古屋市立大学 大学院薬学研究科 細子分子薬効解析学分野 教授(改組)

    2005年4月 名古屋市立大学 大学院薬学研究科長・薬学部長(~2007年3月)

    2014年4月 名古屋市立大学 理事(研究・国際担当)・副学長 現在に至る

    2018年3月 日本薬学会賞受賞「疾患治療標的および創薬標的としてのイオンチャネル分子機能解明」

    2018年4月 名古屋市立大学 大学院薬学研究科 特任教授 現在に至る

研究キーワード

  • カルシウムシグナリング   バイオイメージング   イオントランスポーター   平滑筋   イオンチャネル   

研究分野

  • ライフサイエンス / 薬理学

経歴

  • 1978-1981 名古屋市立大学(薬学部)1981-1996 名古屋市立大学

学歴

  •         - 1976年   東京大学   薬学部   生命薬学

所属学協会

  • 日本神経科学会   日本生理学会   日本平滑筋学会   日本薬理会   日本薬学会   

研究活動情報

論文

書籍

  • 血管平滑節カルシウムチャネルの機能制御とその役割。
    循環器科 1998年
  • 「平滑節」
    薬学必携シリーズ 薬理学、第11章 朝倉書店 1997年
  • 「オータコイド・抗アレルギー薬」
    薬学必携シリーズ 薬理学、第8章 朝倉書店 1997年
  • Kチャネルと薬。
    ファルマシア(セミナー) 1997年
  • Regulation of Ca-dependent K current and action potential shape by intracellular Ca storage sites in some types of smooth muscle cells.
    1996年
  • Noradrenaline-induced Ca-channel current modulation in smooth muscles.
    1996年
  • 心血管以外の臓器に対するKチャネル開口薬の作用。
    治療学 1996年
  • 「下剤と止瀉剤」
    病気とくすり 南山堂 1994年
  • Effects of 9-methyl-7-bromoeudistomin D(MBED), a powerful Ca
    1993年
  • Ca拮抗薬の平滑節Ca電流に対する選択的抑制作用について
    1993年
  • 各種平滑節細胞の興奮性の多様性とその機序について
    日本薬理学会誌(日本薬理学会奨励賞受賞総説) 1993年
  • Electrical properties of iris sphincter.
    1992年
  • 「平滑節組織及び単離細胞からの電気現象誘導法」
    生物薬科学実験講座 臓器機能測定法(]G0003[)広川書店 1992年
  • Measurement of noninactivating calcium current in smooth muscle cells.
    1991年
  • A comparative study about voltage-dependent Ca currents in smooth muscle cells isolated from several tissues.
    1989年

MISC

  • Roles of Ca2+ release-activated Ca2+ channels on cell cycle progression in bovine brain capillary endothelial cells
    Hiroaki Kito; Hisao Yamamura; Yoshiaki Suzuki; Susumu Ohya; Kiyofumi Asai; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 132P -132P 2014年
  • The characteristics of TMEM1 6A splicing variants functionally expressed in mice portal vein
    Junya Ohshiro; Takanori Saeki; Hisao Yamamura; Yoshiaki Suzuki; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 132P -132P 2014年
  • Expression analyses of TMEM16A in portal veins of portal hypertensive model mice
    Rubii Kondo; Junya Ohshiro; Yoshiaki Suzuki; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 133P -133P 2014年
  • The regulatory mechanism underlying the enhanced expression of BK channel by testosterone
    Regis Azizieh; Akinori Ohno; Susumu Ohya; Yoshiaki Suzuki; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 200P -200P 2014年
  • Overactive bladder mediated by accelerated Ca2+ influx mode of Na+/Ca2+ exchanger in smooth muscle
    Hisao Yamamura; William C. Cole; Satomi Kita; Shingo Hotta; Hidemitchi Murata; Yoshiaki Suzuki; Susumu Ohya; Takahiro Iwamoto; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 109P -109P 2014年
  • Involvement of inward rectifying K+ channel (K(ir)2.1) in vascular tone regulation of mesenteric artery in renovascular hypertensive mice
    Minami Hattori; Fumito Maruyama; Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 161P -161P 2014年
  • Functional expression of Ca2+-activated Cl- (TMEM16B) channel in rat pineal glands
    Kaori Nishimura; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 122P -122P 2014年
  • Modulatory effects of a novel BK alpha splice variant on BK channel functions
    Yoshiaki Suzuki; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 137P -137P 2014年
  • Intracellular Ca2+ regulation analysis in mice non-pregnant and pregnant myometrial smooth muscle cells
    Katsuhito Matsuki; Masashi Takemoto; Yoshiaki Suzuki; Susumu Ohya; Hiroshi Takeshima; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 109P -109P 2014年
  • Clarify the molecular entity of chloride channels in human chondrosarcoma cell line (OUMS-27)
    Takashi Kurita; Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 116P -116P 2014年
  • Development of airway clearance assessment of fluorescent beads
    Teruya Ohba; Eiji Sawada; Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 124 139P -139P 2014年
  • SOC channels regulate histamine-induced Ca2+ influx in human chondrocytes
    Munenori Inayama; Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 102P -102P 2013年
  • Up-regulation of the positive regulators of k(ca)3.1 K+ channel in auricular CD4(+) cells of DTH mice model
    Susumu Ohya; Miki Matsui; Hiroaki Kito; Sayuri Horiba; Erina Nakamura; Masanori Fujii; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 195P -195P 2013年
  • Translation of Ca2+ clock to electrical signal in HEK293 cells heterologously co-expressing ryanodine receptor and Ca2+ activated CI-channel, TMEM16A
    Junya Ohshiro; Keigo Hashidume; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 117P -117P 2013年
  • A novel splice variant of Bk alpha subunit from a human chondrosarcoma cell line OUMS-27
    Yoshiaki Suzuki; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 113P -113P 2013年
  • Spontaneous electrical activity and hyperpolarization activating cation channel in rat pinealocyetes
    Keiko Kiyota; Makoto Muramatsu; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 99P -99P 2013年
  • Membrane hyperpolarization due to ATP-sensitive K(+)channel openers facilitated ciliary beating in mouse airway ciliated cells
    Teruya Ohba; Eiji Sawada; Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 112P -112P 2013年
  • Roles of Ca2+ release-activated Ca2+(CRAC) channels on cell cycle progression and proliferation in bovine brain capillary endothelial cells
    Hiroaki Kito; Hisao Yamamura; Susumu Ohya; Kiyofumi Asai; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 91P -91P 2013年
  • New screening system of blockers selective to Kv channels using recombinant cell line dying upon single action potential
    Masato Fujii; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 121 130P -130P 2013年
  • Development of recombinant cell line dying upon single action potential occurrence for the assay of compounds acting on voltage-dependent K+ (Kv) channels
    Masato Fujii; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 95P -95P 2012年
  • TRIC-A channels regulate blood pressure in vascular smooth muscle
    Daiju Yamazaki; Satomi Kita; Miyuki Nishi; Yuji Imaizumi; Takahiro Iwamoto; Hiroshi Takeshima JOURNAL OF PHARMACOLOGICAL SCIENCES 118 77P -77P 2012年
  • Changes in contribution of inward rectifying K+ channel (Kir2.1) to vascular smooth muscle tone in small artery of renovascular hypertensive model mice
    Fumito Maruyama; William C. Cole; Hideaki Ishii; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 84P -84P 2012年
  • Role of K(Ca)3.1 K+ channel in T-lymphocyte function of delayed-type hypersensitivity model mice
    Susumu Ohya; Sayuri Horiba; Erina Nakamura; Miki Matsui; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 90P -90P 2012年
  • Caveola regulates vascular smooth muscle cell function via BK-Cav1.2 complex.
    Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 92P -92P 2012年
  • Down-regulation of the large-conductance Ca2+-activated K plus channel, KCa1.1 in the prostatic stromal cells of benign prostate hyperplasia
    Satomi Niwa; Susumu Ohya; Yoshiyuki Kojima; Shoichi Sasaki; Hisao Yamamura; Motomu Sakuragi; Kenjiro Kohri; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 93P -93P 2012年
  • Roles of Ca2+ release-activated Ca2+ (CRAG) channels on cell proliferation in bovine brain capillary endothelial cells
    Hiroaki Kito; Daiju Yamazaki; Susumu Ohya; Hisao Yamamura; Kiyofumi Asai; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 83P -83P 2012年
  • Hyperpolarization-activated Cyclic Nucleotide-gated Channels in rat pineal gland
    Keiko Kiyota; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 69P -69P 2012年
  • Relation between membrane potential and intracellular Ca2+ concentration in mouse airway ciliated cell
    Teruya Ohba; Eiji Sawada; Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 130P -130P 2012年
  • Dominant-Negative, Spliced Variant of the Intermediate-Conductance Ca2+-Activated K+ Channel, K(Ca)3.1 in Lymphoid Cells
    Susumu Ohya; Satomi Niwa; Ayano Yanagi; Yuka Fukuyo; Hisao Yamamura; Yuji Imaizumi BIOPHYSICAL JOURNAL 102 (3) 691A -692A 2012年01月
  • Expression of TMEM16 family and Ca2+ activated Cl- channel activity in smooth muscle cells
    Junya Ohshiro; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 118 91P -91P 2012年
  • TRIC-A Channel and Blood Pressure Regulation
    Daiju Yamazaki; Satomi Kita; Shinji Komazaki; Daisuke Naitou; Miyuki Nishi; Hisao Yamamura; Yuji Imaizumi; Takahiro Iwamoto; Hiroshi Takeshima BIOPHYSICAL JOURNAL 100 (3) 249 -250 2011年02月
  • Caveola promotes BK-VDCC complex in vascular smooth muscle cells
    Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 87P -87P 2011年
  • Overview of ion channels as a target for drug discovery and novel screening methods
    Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 55P -55P 2011年
  • Physiological role of the dominant-negative K(Ca)3.1 channel isoform in mice thymocytes
    Susumu Ohya; Yuka Fukuyo; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 125P -125P 2011年
  • Regulation of cytosolic Ca2+ signal and melatonin secretion by action potentials in rat pineal glands
    Keiko Kiyota; Makoto Muramatsu; Hisao Yamamura; Hiroya Mizutani; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 188P -188P 2011年
  • Inward rectifier K+(Kir2.1) channel as a factor regulating cell death in bovine brain endothelial cells
    Hiroaki Kito; Daiju Yamazaki; Hisao Yamamura; Susumu Ohya; Kiyofumi Asai; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 107P -107P 2011年
  • Molecular mechanisms underlying the modulation of Kv1.3 channel activity by phosphatidylinositol 4,5-bisphosphate
    Takahiro Muramoto; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 123P -123P 2011年
  • Functional analysis of ion channels in murine airway ciliated cell
    Eiji Sawada; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 80P -80P 2011年
  • Expression and function of ryanodine receptor type 3 in nonpregnant and pregnant myometrium of the mice
    Masashi Takemoto; Hisao Yamamura; Susumu Ohya; Hiroshi Takeshima; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 100P -100P 2011年
  • Expression of TMEM16 family as molecular counterparts of Ca2+ activated Cl- channel in vascular smooth muscle cells
    Junya Ohshiro; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 112P -112P 2011年
  • A novel cell system of autoclasis with single action potential for screening of drug development targeting on ion channels
    Masato Fujii; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 82P -82P 2011年
  • Keiko Kiyota; Makoto Muramatsu; Hisao Yamamura; Hiroya Mizutani; Susumu Ohya; Yuji Imaizumi NEUROSCIENCE RESEARCH 68 E114 -E114 2010年
  • Gender differences in ion channel expression profile in rat amygdala complex
    Masato Fujii; Akitoshi Ohno; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 235P -235P 2010年
  • Molecular assembly within Ca2+ spark microdomain in vascular smooth muscle cells
    Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 85P -85P 2010年
  • Intermediate-conductance Ca2+-activated K+ channel, K(Ca)3.1 as a novel therapeutic target for benign prostatic hyperplasia
    Satomi Niwa; Susumu Ohya; Yoshiyuki Kojima; Shoichi Sasaki; Motomu Sakuragi; Kenjiro Kohri; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 94P -94P 2010年
  • Masato Fujii; Akitoshi Ohno; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi NEUROSCIENCE RESEARCH 68 E111 -E111 2010年
  • Roles of Na+/Ca+ exchanger reverse mode in the regulation of urinary bladder functions
    Hidemichi Murata; Shingo Hotta; Hisao Yamamura; Susumu Ohya; Satomi Kita; Takahiro Iwamoto; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 89P -89P 2010年
  • Molecular pharmacological studies on the intermediate-conductance Ca2+ -activated K+ channel, K(Ca)3.1 in auricular lymphocytes of delayed-type hypersensitivity (DTH) model mice
    Susumu Ohya; Erina Nakamura; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 105P -105P 2010年
  • Visualization of BK-VDCC complex in vascular smooth muscle cells
    Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 59P -59P 2010年
  • Accelerated Ca2+ entry by membrane hyperpolarization due to Ca2+-activated K+ channel activation in response to histamine in chondrocytes
    Kenji Funahashi; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 112P -112P 2010年
  • Cytosolic Ca2+ mobilization induced by L-glutamate in rat pinealocytes
    Makoto Muramatsu; Hisao Yamamura; Hiroya Mizutani; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 112 102P -102P 2010年
  • Androgen regulates BK channel expression by the ubiqutin-proteosomal pathway in rat vas deferens smooth muscle
    Akitoshi Ohno; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 67P -67P 2009年
  • FUNCTIONAL ROLES OF Na+/Ca2+ EXCHANGER (NCX) IN SPONTANEOUS CONTRACTIONS IN MOUSE URINARY BLADDER SMOOTH MUSCLE
    Hidemichi Murata; Shingo Hotta; Hisao Yamamura; Susumu Ohya; Takahiro Iwamoto; Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 237 -237 2009年
  • TIRF imaging of Ca2+ spark microdomain in vascular smooth muscle cells
    Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 119P -119P 2009年
  • LARGE-CONDUCTANCE Ca2+-ACTIVATED K+ CHANNEL REGULATES SPONTANEOUS Ca2+ OSCILLATIONS IN RAT PINEALOCYTES
    Makoto Muramatsu; Hiroya Mizutani; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 243 -243 2009年
  • ROLE OF THE INTERMEDIATE-CONDUCTANCE Ca2+-ACTIVATED K+ CHANNEL, K(Ca)3.1 SPLICED ISOFORM
    Susumu Ohya; Satomi Niwa; Ayano Yanagi; Erina Nakamura; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 255 -255 2009年
  • VISUALIZATION OF BK CHANNEL AND Ca2+ CHANNEL COMPLEX BY TIRF IMAGING
    Yoshiaki Suzuki; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 401 -401 2009年
  • Mechanisms underlying subunit selective activation of BK channel by DiBAC(4)(3)
    Keisuke Fujitaka; Takashi Morimoto; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 90P -90P 2009年
  • Makoto Muramatsu; Hisao Yamamura; Hiroya Mizutani; Susumu Ohya; Yuji Imaizumi NEUROSCIENCE RESEARCH 65 S136 -S136 2009年
  • Molecular imaging of BK channel and Ca2+ channel complex by TIRF analysis
    Yoshiaki Suzuki; Hisao Yamamura; Chikako Ikeda; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 89P -89P 2009年
  • Masato Fujii; Akitoshi Ohno; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi NEUROSCIENCE RESEARCH 65 S136 -S137 2009年
  • Novel spliced variants of the intermediate-conductance Ca2+-activated K+ channel, K(Ca)3.1
    Susumu Ohya; Satomi Niwa; Ayano Yanagi; Erina Nakamura; Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 103P -103P 2009年
  • Functional roles of ryanodine receptor type 3 in the membrane potential regulation in vascular smooth muscle
    Daiki Kato; Hisao Yamamura; Susumu Ohya; Hiroshi Takeshima; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 74P -74P 2009年
  • MOLECULAR IMAGING ANALYSES OF Ca2+ SIGNALING UNITS REGULATING THE EXCITABILITY AND TONE OF VASCULAR SMOOTH MUSCLE CELLS
    Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 63 -63 2009年
  • GENDER DIFFERENCE IN BK CHANNEL EXPRESSION IN AMYGDALA OF RAT BRAIN
    Masato Fujii; Akitoshi Ohno; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 255 -255 2009年
  • MEMBRANE HYPERPOLARIZATION FACILITATES Ca2+ INFLUX IN HUMAN CHONDROSARCOMA CELL LINE (OUMS-27)
    Kenji Funahashi; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 243 -243 2009年
  • TIRF IMAGING OF Ca2+ SPARK MICRODOMAIN IN VASCULAR SMOOTH MUSCLE CELLS
    Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHYSIOLOGICAL SCIENCES 59 237 -237 2009年
  • Cytosolic Ca2+ mobilization induced by nicotine in rat pinealocytes
    Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 99P -99P 2009年
  • Intercellular electrical communication in pacemaker model
    Keigo Hashidume; Taisuke Kimura; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 109 92P -92P 2009年
  • Modulation by CD3/CD28 activation on Kv1.3 K+ current in human leukemia Jurkat cells
    Yuichiro Matsushita; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 106 199P -199P 2008年
  • Gender difference of large conductance Ca2+ activated K+ channels in rat amygdala
    Akitoshi Ohno; Susumu Ohya; Hisao Yamamura; Yuji Imaizumi NEUROSCIENCE RESEARCH 61 S214 -S214 2008年
  • Mechanism underlying enhanced spontaneous contractions in urinary bladder smooth muscle of Na+/Ca2+ exchanger (NCX) overexpressing mice
    Hidemichi Murata; Shingo Hotta; Hisao Yamamura; Susumu Ohya; Takahiro Iwamoto; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 106 118P -118P 2008年
  • Functional expression of large-conductance Ca2+-activated K+ channel in rat pinealocytes
    Hisao Yamamura; Hiroya Mizutani; Makoto Muramatsu; Susumu Ohya; Yuji Imaizumi NEUROSCIENCE RESEARCH 61 S59 -S59 2008年
  • TIRF imaging of BK channel molecules
    Chikako Ikeda; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 106 73P -73P 2008年
  • TIRF imaging of local Ca2+ transients in smooth muscle cells
    Hisao Yamamura; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 106 97P -97P 2008年
  • Molecular imaging analyses of functional interaction between ion channels and regulatory proteins in subplasmalemmal microdomains
    Yuji Imaizumi; Chikako Ikeda; Hisao Yamamura; Susumu Ohya JOURNAL OF PHARMACOLOGICAL SCIENCES 106 46P -46P 2008年
  • Modulated functions of K+ channels in renal artery smooth muscles of Dahl salt-sensitive rat
    Kazunobu Ogiwara; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 106 82P -82P 2008年
  • Effects of niflumic acid on ion channels in human chondrosarcoma cell line (OUMS-27)
    Kenji Funahashi; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 106 84P -84P 2008年
  • Molecular mechanism of beta subunit-selective BK channel activation by DiBAC(4)(3)
    Takashi Morimoto; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 67P -67P 2007年
  • Functional roles of Na+/Ca2+ exchanger on the regulation of Ca2+ activated K+ channels in vascular smooth muscle
    Hidemichi Murata; Hisao Yamamura; Susumu Ohya; Takahiro Iwamoto; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 85P -85P 2007年
  • Histamine induces membrane hyperpolarization via stimulation of Ca2+ activated K+ channels in human chondrosarcoma cell line (OUMS-27)
    Kenji Funahashi; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 166P -166P 2007年
  • The excess membrane hyperpolarization induced by K(ir)2.1 activation causes brain capillary endothelial cell death
    Daiju Yamazaki; Hisao Yamamura; Susumu Ohya; Katsuhiko Muraki; Kiyofumi Asai; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 96P -96P 2007年
  • Changes in Ca2+ mobilization in urinary bladder smooth muscle overexpressing Na+/Ca2+ exchanger (NCX).
    Shingo Hotta; Hidemichi Murata; Hisao Yamamura; Susumu Ohya; Takahiro Iwamoto; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 52P -52P 2007年
  • Spontaneous Ca2+ transients from sarcoplasmic reticulum and mitochondria in P19CL6 cells
    Yuko Hori; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 98P -98P 2007年
  • Visualization of Ca2+-induced Ca2+ release in smooth muscle cells using total internal reflection fluorescence microscope
    Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 109P -109P 2007年
  • Gene expression of K+ and Ca2+ channels in human prostate carcinoma
    Susumu Ohya; Satomi Niwa; Akitoshi Ohno; Yoshiyuki Kojima; Shoichi Sasaki; Kenjiro Kohri; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 172P -172P 2007年
  • Functional expression of Ca2+ activated Cl- channels in cultured smooth muscle cells of rat pulmonary artery
    Haruna Itoda; Hisao Yamamura; Susumu Ohya; Yuji Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 103 205P -205P 2007年
  • Two types of K+ channels regulate proliferation and death of bovine brain endothelial cells
    Yamazaki Daiju; Ohya Susumu; Muraki Katsuhiko; Asai Kiyofumi; Imaizumi Yuji ACTA PHARMACOLOGICA SINICA 27 191 -191 2006年07月
  • Sarcoplasmic reticulum and membrane events in smooth muscle cells
    Yuji Imaizumi ACTA PHARMACOLOGICA SINICA 27 18 -18 2006年07月
  • The contribution of ryanodine receptor type 2 to E-C coupling and the regulation of resting tone in urinary bladder myocytes
    Shingo Hotta; Kozo Morimura; Susumu Ohya; Katsuhiko Muraki; Hiroshi Takeshima; Yuji Imaizumi ACTA PHARMACOLOGICA SINICA 27 395 -395 2006年07月
  • Down-regulation of intermediate conductance Ca2+ activated K+ channel in smooth muscle of voltage dependent Ca2+ channel beta(3) subunit deficient mouse
    K Morimura; S Ohya; H Yamamura; M Murakami; K Muraki; K Nunoki; T Yanagisawa; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 121P -121P 2006年
  • Inward rectifier K+ channel regulates cell death in bovine capillary endothelial cells
    D Yamazaki; S Ohya; K Muraki; K Asai; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 76P -76P 2006年
  • The regulation of large conductance Ca2+-activated K+ channel expressions brings spontaneous contractions in vas deference from castrated-rat
    A Ohno; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 116P -116P 2006年
  • Pimaric acid modulate voltage-gated K+ channels by binding its activation gate
    K Sakamoto; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 127P -127P 2006年
  • Regulation of gastrointestinal pacemaker activity via 5-HT3 induced Ca2+ influx
    Hong-Nian Liu; Susumu Ohya; Yuji Imaizumi; Shinsuke Nakayama JOURNAL OF PHARMACOLOGICAL SCIENCES 101 69 -69 2006年
  • Effects of 4 alpha-phorbol 12,13-didecanoate, a potent activator of Trpv4, on intracellular Ca2+ concentration and membrane currents in rat aortic myocytes
    R Tanaka; K Muraki; S Ohya; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 110P -110P 2006年
  • The pH sensitivity of the human HCN3 channel
    H Yamamura; N Itazu; Y Matsuoka; S Ohya; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 124P -124P 2006年
  • Cell-cycle dependent regulation of small-conductance Ca(2+-)activated K+ channel activity in Jurkat T-lymphocytes
    T Morimoto; S Ohya; H Hayashi; K Muraki; K Onozaki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 128P -128P 2006年
  • Ca2+ mobilization via ryanodine receptor type 2 in urinary bladder smooth muscle
    S Hotta; K Morimura; S Ohya; K Muraki; H Takeshima; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 100 75P -75P 2006年
  • L Chilton; S Ohya; D Freed; E George; Drobic, V; Y Shibukawa; KA MacCannell; Y Imaizumi; RB Clark; IMC Dixon; WR Giles AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 288 (6) H2931 -H2939 2005年06月
  • Novel mechanism for enhancement of Ca2+ response to ATP in bovine brain capillary endothelial cells
    Y Imaizumi; D Yamazaki; M Aoyama; S Ohya; K Muraki; K Asai FASEB JOURNAL 19 (4) A517 -A517 2005年03月
  • 12,14-Dichrolodehydroabietic acid, a novel opener of mitochondrial large conductance Ca2+-activated K+ channels
    K Sakamoto; S Ohya; K Muraki; T Ohwada; Y Imaizumi BIOPHYSICAL JOURNAL 88 (1) 441A -442A 2005年01月
  • The mechanisms of cardioprotection induced by a novel opener of large conductance Ca2+-activated K+ channels
    K Sakamoto; S Ohya; K Muraki; T Ohwada; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 97 83P -83P 2005年
  • Large-conductance Ca2+-activated K+ channel beta 1 subunit in cardiac mitochondria and cardioprotective effects of 17 beta-estradiol
    S Ohya; Y Kuwata; K Sakamoto; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 97 132P -132P 2005年
  • Local Ca2+ control and Ca2+ wave during E-C coupling in mouse urinary bladder smooth muscle cells
    K Morimura; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 97 245P -245P 2005年
  • A model for electrical pacemaking activity by functional coupling between cloned ryanodine receptor and small-conductance Ca2+-activated K+ channel
    T Kimura; T Goto; S Hotta; S Ohya; K Muraki; C Wayne; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 97 112P -112P 2005年
  • The functional analyses of ryanodine receptor type 2 (RyR2) in excitation-contraction coupling using urinary bladder smooth muscle of RyR2 heterozygous KO mouse
    S Hotta; K Morimura; S Ohya; K Muraki; H Takeshima; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 97 75P -75P 2005年
  • Large-conductance Ca2+-activated K+ channel beta 1 subunit in cardiac mitochondria and activation by 17 beta-estradiol
    S Ohya; Y Kuwata; K Sakamoto; K Muraki; Y Imaizumi BIOPHYSICAL JOURNAL 88 (1) 441A -441A 2005年01月
  • Knockdown of small conductance Ca2+-activated K+ channel (SK2) suppressed the positive feedback regulation of intracellular Ca2+ in t-BBEC 117
    D Yamazaki; M Aoyama; S Ohya; K Muraki; K Asai; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 97 135P -135P 2005年
  • Hormonal regulation of large conductance Ca2+-activated K+ channel expression in rat vas deferens
    A Ohno; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 97 106P -106P 2005年
  • The activation of voltage-gated K+ channels by rosin acid
    K Sakamoto; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 94 115P -115P 2004年
  • Positive feedback mechanism in the regulation of [Ca2+](i) by activation of small-conductance Ca2+-activated K+ channel (SK2) in t-BBEC 117
    D Yamazaki; M Aoyama; S Ohya; K Muraki; K Asai; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 94 172P -172P 2004年
  • Testosterone regulates expression and function of Kv4.3 encoding A-type K+ channel
    K Ito; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 94 141P -141P 2004年
  • Properties of cultured cells from gastrointestinal stromal tumors (GIST)
    S Furuzono; S Ohya; S Inoue; A Nakao; Y Imaizumi; S Nakayama JOURNAL OF PHARMACOLOGICAL SCIENCES 94 256P -256P 2004年
  • Contribution of voltage dependent Ca2+ channel beta3 subunit to the regulation of Ca2+ release and the excitation-contraction coupling in mice urinary bladder smooth muscle
    Y Imaizumi; K Morimura; H Yamamura; M Murakami; S Ohya; K Nunoki; K Muraki; Flockerzi, V; T Yanagisawa BIOPHYSICAL JOURNAL 86 (1) 113A -113A 2004年01月
  • Contribution of intermediate conductance Ca2+ activated K+ channel to membrane excitability of murine urinary bladder smooth muscle cell
    K Morimura; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 94 141P -141P 2004年
  • (R)-methanandamide as an opener of large conductance Ca2+ activated K+ channel
    H Sade; K Muraki; S Ohya; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 94 125P -125P 2004年
  • Cell cycle dependent regulation of small conductance Ca2+-activated K+ channel (SK2) activity in Jurkat T-lymphocytes
    T Morimoto; S Ohya; H Hayashi; K Muraki; K Onozaki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 94 204P -204P 2004年
  • Regulation of Kv4.3 channels by Ca2+-calmodulin-dependent protein kinase II
    GP Sergeant; S Ohya; GC Amberg; Rehill, JR; B Horowitz; Y Imaizumi; KM Sanders; SD Koh BIOPHYSICAL JOURNAL 84 (2) 415A -415A 2003年02月
  • BK channel opening properties of pimarane compounds and their channel selectivity
    Y Imaizumi; K Sakamoto; S Ohya; K Muraki; T Nonomura; T Ohwada BIOPHYSICAL JOURNAL 84 (2) 92A -92A 2003年02月
  • Inducible expression of edg receptors in rat pial vasculature by cell-cultivation.
    K Muraki; T Itoh; S Ohya; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 153P -153P 2003年
  • Measurement of membrane potential from colonies of HEK293 cells transiently expressing ion channels by use of voltage-sensitive fluorescent dye.
    A Hotta; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 245P -245P 2003年
  • Contribution of K+ channels to proliferation and cell death of non-excitable cells and pharmacology of related drugs.
    Y Imaizumi; S Ohya; T Morimoto; K Muraki JOURNAL OF PHARMACOLOGICAL SCIENCES 91 32P -32P 2003年
  • Confirmation of a 3 : 1 stoichiometry of cardiac Na+-Ca2+ exchanger.
    J Kimura; M Hinata; H Yamamura; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 22P -22P 2003年
  • Two arginines in C-terminal domain are essential for the voltage-dependent regulation of A-type K+ current through Kv4 channel subfamily.
    N Hatano; S Ohya; K Muraki; RB Clark; WR Giles; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 243P -243P 2003年
  • Epithelial Na+ channel delta subunit isolated from human trigeminal ganglion.
    H Yamamura; S Ugawa; T Ueda; K Muraki; Y Imaizumi; S Shimada JOURNAL OF PHARMACOLOGICAL SCIENCES 91 94P -94P 2003年
  • Co-expression of ryanodine receptor type3 and Ca2+ activated K+ channels in HEK293 cells.
    T Goto; A Yamada; K Sakamoto; W Chen; S Ohya; K Muraki; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 242P -242P 2003年
  • Mechanisms underlying Ca2+ increase induced by hypotonic stress in human umbilical vein endothelial cells.
    T Itoh; K Muraki; S Ohya; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 95P -95P 2003年
  • Possible role of TASK in acidic pH induced depolarization in WKY and SHR aortic smooth muscle cells.
    H Kiyoshi; M Kitsukawa; S Saito; S Ohya; K Muraki; Y Ohizumi; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 243P -243P 2003年
  • Ca2+ imaging of urinary bladder myocyte from voltage dependent Ca2+ channel beta(3) subunit deficient mouse.
    K Morimura; M Murakami; H Yamamura; S Ohya; K Muraki; K Nunoki; T Yanagisawa; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 243P -243P 2003年
  • Calcium movement underlying intestinal pacemaker activity.
    S Nakayama; M Aoyama; J Wang; S Ohya; Y Ito; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 60P -60P 2003年
  • Abietane compounds as a new class of large conductance Ca2+ activated K+ channel openers.
    K Sakamoto; T Nonomura; A Hotta; S Ohya; K Muraki; T Ohwada; Y Imaizumi JOURNAL OF PHARMACOLOGICAL SCIENCES 91 245P -245P 2003年
  • Functional importance of mitochondrial Ca2+ uptake during depolarization in smooth muscle cells of guinea pig urinary bladder
    H Yamamura; K Muraki; Y Imaizumi JAPANESE JOURNAL OF PHARMACOLOGY 88 174P -174P 2002年
  • Possible involvement of IP3 formation in depolarization-induced Ca2+ mobilization in porcine coronary arterial smooth muscle cells
    Y Imaizumi; H Yamamura; K Muraki JAPANESE JOURNAL OF PHARMACOLOGY 88 174P -174P 2002年
  • Novel openers of large conductance Ca2+ activated K+ channels derived from resin
    K Sakamoto; A Yamada; A Hotta; D Yamazaki; S Ohya; K Muraki; T Ohwada; Y Imaizumi JAPANESE JOURNAL OF PHARMACOLOGY 88 160P -160P 2002年
  • Functional analysis of cytoplasmic C-terminal domain in Kv4.3 K+ channel subtype by use of deletion mutants.
    N Hatano; S Ohya; Y Imaizumi JAPANESE JOURNAL OF PHARMACOLOGY 88 158P -158P 2002年
  • The functional interaction between IP3 receptors and ryanodine receptor type 3 expressed in HEK293 cells
    T Goto; A Yamada; C Wayne; S Ohya; K Muraki; Y Imaizumi JAPANESE JOURNAL OF PHARMACOLOGY 88 218P -218P 2002年
  • Characteristics of non-selective cation currents activated by sphingosine-1-phosphate in human endothelial cells
    K Muraki; T Ito; Y Imaizumi JAPANESE JOURNAL OF PHARMACOLOGY 88 271P -271P 2002年
  • Aki Yamada; Norikazu Gaja; Susumu Ohya; Katsuhiko Muraki; Hiroshi Narita; Tomohiko Ohwada; Yuji Imaizumi ┣DBJpn. J. Pharmacol.(/)-┫DB 86 (3) 342 -350 2001年
  • Ca2+ images during membrane hyperpolarization in vascular smooth muscle cells
    Y Imaizumi; H Yamamura; Y Ohi; K Muraki; M Watanabe JOURNAL OF VASCULAR RESEARCH 36 (5) 421 -421 1999年09月
  • Ca2+ spark as a regulator of ion channel activity
    Y Imaizumi; Y Ohi; H Yamamura; S Ohya; K Muraki; M Watanabe JAPANESE JOURNAL OF PHARMACOLOGY 80 (1) 1 -8 1999年05月
  • Regulation of vascular tone by purinoceptor-activation on vascular smooth muscle and endothelial cells
    K Muraki; Y Ohi; Y Imaizumi; M Watanabe BIOPHYSICAL JOURNAL 76 (1) A349 -A349 1999年01月
  • Ca2+ sparks and spontaneous transient K+ current in guinea pig urinary bladder smooth muscle cells
    Y Imaizumi; Y Ohi; H Yamamura; M Watanabe NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 358 (1) R697 -R697 1998年
  • Molecular cloning and functional expression of A-type K+ channel subtypes in rat smooth muscle.
    S Ohya; M Tanaka; T Oku; Y Asai; M Watanabe; Y Imaizumi NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 358 (1) R706 -R706 1998年
  • Ca2+ imaging with a fast scanning confocal microscope during the action potential in smooth muscle cells.
    Y Imaizumi; Y Torii; Y Ooi; K Muraki; TB Bolton; M Watanabe BIOPHYSICAL JOURNAL 72 (2) THAM9 -THAM9 1997年02月
  • Ca2+-activated Cl channels in cells from tracheal smooth muscle of the guinea-pig.
    Y Imaizumi; S Henmi; K Muraki; M Watanabe BIOPHYSICAL JOURNAL 70 (2) SU208 -SU208 1996年02月
  • QUINIDINE-INDUCED INHIBITION OF A TRANSIENT OUTWARD CURRENT IN RABBIT HEART
    WR GILES; Y IMAIZUMI JOURNAL OF PHYSIOLOGY-LONDON 390 P68 -P68 1987年09月
  • COMPARISON OF K+ CURRENTS IN SINGLE CELLS FROM RABBIT ATRIUM AND VENTRICLE
    Y IMAIZUMI; W GILES BIOPHYSICAL JOURNAL 51 (2) A256 -A256 1987年02月
  • EFFECT OF CA ANTAGONIST AND CALMODULIN INHIBITOR ON CA-DEPENDENT K-CHANNELS IN ISOLATED SMOOTH-MUSCLE CELLS
    T KOJIMA; Y IMAIZUMI; M WATANABE JAPANESE JOURNAL OF PHARMACOLOGY 40 P242 -P242 1986年
  • CELLULAR MECHANISMS OF SUPERSENSITIVITY TO ACETYLCHOLINE AND POTASSIUM-ION AFTER CILIARY GANGLIONECTOMY IN THE RAT IRIS SPHINCTER MUSCLE
    H BANNO; Y IMAIZUMI; M WATANABE JAPANESE JOURNAL OF PHARMACOLOGY 40 P209 -P209 1986年
  • CA-45 UPTAKE INHIBITION AND RECEPTOR-BINDING OF A NEW DIHYDROPYRIDINE CA ANTAGONIST, KW-3049
    Y OKADA; R ITO; Y IMAIZUMI; M WATANABE FOLIA PHARMACOLOGICA JAPONICA 86 (5) P138 -P138 1985年
  • NEURO-EFFECTOR TRANSMISSION IN THE RAT IRIS SPHINCTER MUSCLE
    H BANNO; Y IMAIZUMI; M WATANABE FOLIA PHARMACOLOGICA JAPONICA 85 (2) P21 -P22 1985年
  • EFFECTS OF ACETYLCHOLINE AND SEROTONIN ON K-PERMEABILITY IN SMOOTH-MUSCLE CELL-MEMBRANE OF CANINE TRACHEA
    Y IMAIZUMI; M WATANABE FOLIA PHARMACOLOGICA JAPONICA 85 (2) P21 -P21 1985年
  • EFFECT OF CA-BLOCKERS ON 86RB-EFFLUX AND 45CA-UPTAKE IN ISOLATED RABBIT AORTA DURING HIGH K STIMULATION
    Y IMAIZUMI; Y OKADA; M WATANABE JAPANESE JOURNAL OF PHARMACOLOGY 39 P397 -P397 1985年
  • EFFECT OF SODIUM REMOVAL ON THE RELAXATION INDUCED BY ACETYLCHOLINE OR OTHER DRUGS IN RAT IRIS DILATOR MUSCLE
    K SHIBATA; Y IMAIZUMI; M WATANABE JAPANESE JOURNAL OF PHARMACOLOGY 36 P61 -P61 1984年
  • ANOMALOUS STABILIZING ACTION OF CA ON SPHINCTER SMOOTH-MUSCLE OF THE RAT IRIS
    Y IMAIZUMI; H BANNO; M WATANABE PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 400 (3) 332 -334 1984年
  • DEVELOPMENTAL PHARMACOLOGY OF CYCLIC-AMP RELATED RELAXATION IN CHICK JUGULAR VEIN
    M BABA; Y IMAIZUMI; M WATANABE JAPANESE JOURNAL OF PHARMACOLOGY 36 P293 -P293 1984年
  • A DEVELOPMENTAL-STUDY OF THE SENSITIVITY OF THE RAT TRACHEA TO ACETYLCHOLINE, POTASSIUM AND SEROTONIN
    K SHIBATA; Y IMAIZUMI; M WATANABE FOLIA PHARMACOLOGICA JAPONICA 81 (2) P35 -P35 1983年
  • EFFECTS OF TETRAETHYLAMMONIUM, 4-AMINOPYRIDINE, AND PROCAINE ON CONTRACTILE RESPONSE TO 5-HT IN CANINE TRACHEAL SMOOTH-MUSCLE
    T ISHIKAWA; Y IMAIZUMI; M WATANABE FOLIA PHARMACOLOGICA JAPONICA 80 (3) P46 -P46 1982年

受賞

  • 2018年03月 日本薬学会 日本薬学会賞
     疾患治療標的および創薬標的としてのイオンチャネル分子機能解明 
    受賞者: 今泉 祐治
  • 1992年03月 日本薬理学会 日本薬理学会学術奨励賞
     各種平滑筋細胞の興奮性の多様性とその機序について

共同研究・競争的資金等の研究課題

  • 新規メカニズム導入によるイオンチャネル作用薬の効率的探索法の開発
    研究期間 : 2003年 -2004年
  • 細胞内カルシウムによるイオンチャネル活性制御機構と関連疾患の治療薬探索
    研究期間 : 2002年 -2004年
  • 心血管系病態でのイオンチャネル発現変化とその機構
    研究期間 : 1998年 -1999年
  • 電位依存性一過性Kチャネルのアラキドン酸感受性と遺伝子解析
    研究期間 : 1998年 -1999年
  • 気道平滑筋細胞のカルシウム依存性クロライドチャネルと気道過敏症
    研究期間 : 1996年 -1997年
  • ラット胃セロトニン受容体に関連した低分子量タンパクの遺伝子クロ-ニングと発現
    研究期間 : 1994年 -1995年
  • 各種平滑筋細胞におけるCaチャネル活性調節機構の多様性とそのメカニズム
    研究期間 : 1992年 -1993年
  • 新たな疾患治療を目指したカルシウム活性化カリウムチャネル作用薬の薬効解析と応用
  • 生細胞内オルガネラ膜上タンパク質の一分子可視化技術の開拓
  • トランスポートソームによるペースメーカー活動の発生・調節機構

その他のリンク

researchmap



Copyright © MEDIA FUSION Co.,Ltd. All rights reserved.