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立野 一郎タツノ イチロウ

所属部署医学研究科細菌学分野
職名講師
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Last Updated :2019/07/06

研究者基本情報

学位

  • 博士(理学), 名古屋大学

所属学協会

  • 日本細菌学会

委員歴

  •   1997年 - 1999年, 日本細菌学会, 一般

研究活動情報

研究分野

  • 基礎医学, 細菌学(含真菌学)

研究キーワード

    細菌

論文

  • Functional Predominance of msr(D), Which Is More Effective as mef(A)-Associated Than mef(E)-Associated, Over mef(A)/mef(E) in Macrolide Resistance in Streptococcus pyogenes., Tatsuno I, Isaka M, Masuno K, Hata N, Matsumoto M, Hasegawa T, Microbial drug resistance (Larchmont, N.Y.), 24, (8) 1089 - 1097,   2018年10月, 査読有り
  • Female GADD34 mice develop age-related inflammation and hepatocellular carcinoma., Nishio N, Hasegawa T, Tatsuno I, Isaka M, Isobe KI, Geriatrics & gerontology international, 17, (12) 2593 - 2601,   2017年12月, 査読有り
  • Characterisation of clinically isolated Streptococcus pyogenes from balanoposthitis patients, with special emphasis on emm89 isolates., Hasegawa T, Hata N, Matsui H, Isaka M, Tatsuno I, Journal of medical microbiology, 66, (4) 511 - 516,   2017年04月, 査読有り
  • Two-Component Systems Involved in Susceptibility to Nisin A in Streptococcus pyogenes., Kawada-Matsuo M, Tatsuno I, Arii K, Zendo T, Oogai Y, Noguchi K, Hasegawa T, Sonomoto K, Komatsuzawa H, Applied and environmental microbiology, 82, (19) 5930 - 5939,   2016年10月, 査読有り
  • The YvqE two-component system controls biofilm formation and acid production in Streptococcus pyogenes., Isaka M, Tatsuno I, Maeyama J, Matsui H, Zhang Y, Hasegawa T, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 124, (7) 574 - 585,   2016年07月, 査読有り
  • Description of the Pathogenic Features of Streptococcus pyogenes Isolates from Invasive and Non-Invasive Diseases in Aichi, Japan., Matsumoto M, Yamada K, Suzuki M, Adachi H, Kobayashi S, Yamashita T, Minagawa H, Tatsuno I, Hasegawa T, Japanese journal of infectious diseases, 69, (4) 338 - 341,   2016年07月, 査読有り
  • Relevance of spontaneous fabT mutations to a streptococcal toxic shock syndrome to non-streptococcal toxic shock syndrome transition in the novel-type Streptococcus pyogenes isolates that lost a salRK., Tatsuno I, Okada R, Matsumoto M, Hata N, Matsui H, Zhang Y, Isaka M, Hasegawa T, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 124, (5) 414 - 424,   2016年05月, 査読有り
  • Predominant role of msr(D) over mef(A) in macrolide resistance in Streptococcus pyogenes., Zhang Y, Tatsuno I, Okada R, Hata N, Matsumoto M, Isaka M, Isobe K, Hasegawa T, Microbiology (Reading, England), 162, (1) 46 - 52,   2016年01月, 査読有り
  • Analysis of the roles of NrdR and DnaB from Streptococcus pyogenes in response to host defense., Zhang Y, Okada R, Isaka M, Tatsuno I, Isobe K, Hasegawa T, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 123, (3) 252 - 259,   2015年03月, 査読有り
  • Emergence of type I restriction modification system-negative emm1 type Streptococcus pyogenes clinical isolates in Japan., Okada R, Matsumoto M, Zhang Y, Isaka M, Tatsuno I, Hasegawa T, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 122, (10) 914 - 921,   2014年10月, 査読有り
  • Simultaneous isolation of emm89-type Streptococcus pyogenes strains with a wild-type or mutated covS gene from a single streptococcal toxic shock syndrome patient., Masuno K, Okada R, Zhang Y, Isaka M, Tatsuno I, Shibata S, Hasegawa T, Journal of medical microbiology, 63, (Pt 4) 504 - 507,   2014年04月, 査読有り
  • Relevance of the two-component sensor protein CiaH to acid and oxidative stress responses in Streptococcus pyogenes., Tatsuno I, Isaka M, Okada R, Zhang Y, Hasegawa T, BMC research notes, 7,   2014年03月, 査読有り
  • Adhesion of enterohemorrhagic Escherichia coli O157:H7 to the intestinal epithelia is essential for inducing secretory IgA antibody production in the intestine of mice., Nagano K, Taguchi K, Tokoro S, Tatsuno I, Mori H, Biological & pharmaceutical bulletin, 37, (3) 409 - 416,   2014年, 査読有り
  • Partial loss of CovS function in Streptococcus pyogenes causes severe invasive disease., Tatsuno I, Okada R, Zhang Y, Isaka M, Hasegawa T, BMC research notes, 6,   2013年03月, 査読有り
  • Characterization of NADase-inactive NAD+ glycohydrolase in Streptococcus pyogenes. , 立野 一郎, Advances in Microbiology, 3, (1) 91 - 100,   2013年, 査読有り
  • Analysis of two-component sensor proteins involved in the response to acid stimuli in Streptococcus pyogenes., Ichikawa M, Minami M, Isaka M, Tatsuno I, Hasegawa T, Microbiology (Reading, England), 157, (Pt 11) 3187 - 3194,   2011年11月, 査読有り
  • Variation in M protein production among Streptococcus pyogenes strains according to emm genotype., Matsumoto M, Suzuki M, Hirose K, Hiramatsu R, Minagawa H, Minami M, Tatsuno I, Okamoto A, Ohta M, Hasegawa T, Microbiology and immunology, 55, (6) 379 - 387,   2011年06月, 査読有り
  • Characterization of Streptococcus pyogenes isolated from balanoposthitis patients presumably transmitted by penile-oral sexual intercourse., Minami M, Wakimoto Y, Matsumoto M, Matsui H, Kubota Y, Okada A, Isaka M, Tatsuno I, Tanaka Y, Hasegawa T, Current microbiology, 61, (2) 101 - 105,   2010年08月, 査読有り
  • NADase as a target molecule of in vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates., Tatsuno I, Isaka M, Minami M, Hasegawa T, BMC microbiology, 10,   2010年05月, 査読有り
  • Detection of invasive protein profile of Streptococcus pyogenes M1 isolates from pharyngitis patients., Hasegawa T, Okamoto A, Kamimura T, Tatsuno I, Hashikawa SN, Yabutani M, Matsumoto M, Yamada K, Isaka M, Minami M, Ohta M, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 118, (3) 167 - 178,   2010年03月, 査読有り
  • Characterization of a virulence-associated and cell-wall-located DNase of Streptococcus pyogenes., Hasegawa T, Minami M, Okamoto A, Tatsuno I, Isaka M, Ohta M, Microbiology (Reading, England), 156, (Pt 1) 184 - 190,   2010年01月, 査読有り
  • Clindamycin-induced CovS-mediated regulation of the production of virulent exoproteins streptolysin O, NAD glycohydrolase, and streptokinase in Streptococcus pyogenes., Minami M, Kamimura T, Isaka M, Tatsuno I, Ohta M, Hasegawa T, Antimicrobial agents and chemotherapy, 54, (1) 98 - 102,   2010年01月, 査読有り
  • The streptococcal inhibitor of complement (SIC) protects Streptococcus pyogenes from bacteriocin-like inhibitory substance (BLIS) from Streptococcus salivarius., Minami M, Ohmori D, Tatsuno I, Isaka M, Kawamura Y, Ohta M, Hasegawa T, FEMS microbiology letters, 298, (1) 67 - 73,   2009年09月, 査読有り
  • Characterization of the NAD-glycohydrolase in streptococcal strains., Tatsuno I, Sawai J, Okamoto A, Matsumoto M, Minami M, Isaka M, Ohta M, Hasegawa T, Microbiology (Reading, England), 153, (Pt 12) 4253 - 4260,   2007年12月, 査読有り
  • The lpf gene cluster for long polar fimbriae is not involved in adherence of enteropathogenic Escherichia coli or virulence of Citrobacter rodentium., Tatsuno I, Mundy R, Frankel G, Chong Y, Phillips AD, Torres AG, Kaper JB, Infection and immunity, 74, (1) 265 - 272,   2006年01月, 査読有り
  • SepZ/EspZ is secreted and translocated into HeLa cells by the enteropathogenic Escherichia coli type III secretion system., Kanack KJ, Crawford JA, Tatsuno I, Karmali MA, Kaper JB, Infection and immunity, 73, (7) 4327 - 4337,   2005年07月, 査読有り
  • IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity., Ogawa M, Suzuki T, Tatsuno I, Abe H, Sasakawa C, Molecular microbiology, 48, (4) 913 - 931,   2003年05月, 査読有り
  • Increased adherence to Caco-2 cells caused by disruption of the yhiE and yhiF genes in enterohemorrhagic Escherichia coli O157:H7., Tatsuno I, Nagano K, Taguchi K, Rong L, Mori H, Sasakawa C, Infection and immunity, 71, (5) 2598 - 2606,   2003年05月, 査読有り
  • Bicarbonate ion stimulates the expression of locus of enterocyte effacement-encoded genes in enterohemorrhagic Escherichia coli O157:H7., Abe H, Tatsuno I, Tobe T, Okutani A, Sasakawa C, Infection and immunity, 70, (7) 3500 - 3509,   2002年07月, 査読有り
  • Complete nucleotide sequence of the prophage VT1-Sakai carrying the Shiga toxin 1 genes of the enterohemorrhagic Escherichia coli O157:H7 strain derived from the Sakai outbreak., Yokoyama K, Makino K, Kubota Y, Watanabe M, Kimura S, Yutsudo CH, Kurokawa K, Ishii K, Hattori M, Tatsuno I, Abe H, Yoh M, Iida T, Ohnishi M, Hayashi T, Yasunaga T, Honda T, Sasakawa C, Shinagawa H, Gene, 258, (1-2) 127 - 139,   2000年11月, 査読有り
  • Isolation and characterization of mini-Tn5Km2 insertion mutants of enterohemorrhagic Escherichia coli O157:H7 deficient in adherence to Caco-2 cells., Tatsuno I, Kimura H, Okutani A, Kanamaru K, Abe H, Nagai S, Makino K, Shinagawa H, Yoshida M, Sato K, Nakamoto J, Tobe T, Sasakawa C, Infection and immunity, 68, (10) 5943 - 5952,   2000年10月, 査読有り
  • SdiA, an Escherichia coli homologue of quorum-sensing regulators, controls the expression of virulence factors in enterohaemorrhagic Escherichia coli O157:H7., Kanamaru K, Kanamaru K, Tatsuno I, Tobe T, Sasakawa C, Molecular microbiology, 38, (4) 805 - 816,   2000年11月, 査読有り
  • toxB gene on pO157 of enterohemorrhagic Escherichia coli O157:H7 is required for full epithelial cell adherence phenotype., Tatsuno I, Horie M, Abe H, Miki T, Makino K, Shinagawa H, Taguchi H, Kamiya S, Hayashi T, Sasakawa C, Infection and immunity, 69, (11) 6660 - 6669,   2001年11月, 査読有り
  • A novel chromosomal locus of enteropathogenic Escherichia coli (EPEC), which encodes a bfpT-regulated chaperone-like protein, TrcA, involved in microcolony formation by EPEC., Tobe T, Tatsuno I, Katayama E, Wu CY, Schoolnik GK, Sasakawa C, Molecular microbiology, 33, (4) 741 - 752,   1999年08月, 査読有り
  • Regulation of virulence factors of enterohemorrhagic Escherichia coli O157:H7 by self-produced extracellular factors., Kanamaru K, Kanamaru K, Tatsuno I, Tobe T, Sasakawa C, Bioscience, biotechnology, and biochemistry, 64, (11) 2508 - 2511,   2000年11月, 査読有り
  • Intersubunit interaction between transmembrane helices of the bacterial aspartate chemoreceptor homodimer., Umemura T, Tatsuno I, Shibasaki M, Homma M, Kawagishi I, The Journal of biological chemistry, 273, (46) 30110 - 30115,   1998年11月, 査読有り
  • Streptococcus pyogenes protein F promotes invasion of HeLa cells., Okada N, Tatsuno I, Hanski E, Caparon M, Sasakawa C, Microbiology (Reading, England), 144 ( Pt 11), 3079 - 3086,   1998年11月, 査読有り
  • Signaling by the Escherichia coli aspartate chemoreceptor Tar with a single cytoplasmic domain per dimer., Tatsuno I, Homma M, Oosawa K, Kawagishi I, Science (New York, N.Y.), 274, (5286) 423 - 425,   1996年10月, 査読有り
  • Complete nucleotide sequence of the prophage VT2-Sakai carrying the verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7 derived from the Sakai outbreak., Makino K, Yokoyama K, Kubota Y, Yutsudo CH, Kimura S, Kurokawa K, Ishii K, Hattori M, Tatsuno I, Abe H, Iida T, Yamamoto K, Onishi M, Hayashi T, Yasunaga T, Honda T, Sasakawa C, Shinagawa H, Genes & genetic systems, 74, (5) 227 - 239,   1999年10月, 査読有り
  • Transmembrane signalling by the chimeric chemosensory receptors of Escherichia coli Tsr and Tar with heterologous membrane-spanning regions., Tatsuno I, Lee L, Kawagishi I, Homma M, Imae Y, Molecular microbiology, 14, (4) 755 - 762,   1994年11月, 査読有り

MISC

  • [Adherence of enterohemorrhagic Escherichia coli O157:H7 to human epithelial cells]., Tatsuno I, Nihon saikingaku zasshi. Japanese journal of bacteriology, 62, (2) 247 - 253,   2007年05月, 査読有り
  • 大腸菌化学感覚レセプターの膜を介した情報伝達機構, 立野一郎, 川岸郁朗, 本間道夫, 日本細菌学会誌, 52, (3) 567 - 581,   1997年

受賞

  • 日本細菌学会黒屋奨学賞

競争的資金

  • 腸管出血性大腸菌0157に関する研究


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