TAKEMURA Syoko

Researcher Information

Research funding number

• 70647049

J-Global ID

• 201101071766984224

Research Interests

• 低体重出生児   血流   神経新生   可塑性   プロテオグリカン   血管新生   細胞外マトリックス   脳室周囲器官   血液脳関門   神経内分泌   

Research Areas

• Life sciences / Neuroanatomy and physiology
• Life sciences / Neuroscience - general

Academic & Professional Experience

• 2021/04 - Today  Nagoya City University Graduate School of Medical SciencesDepartment of Developmental and Regenerative Neurobiology,Institute of Brain Science,Project assistant professor
• 2012/10 - 2021/03  奈良県立医科大学第２解剖学講座（分子機能形態学講座）助教
• 2011/04 - 2013/03  Kyoto Institute of TechnologyGraduate School of Science and Technology博士（学術）取得
• 2011/04 - 2012/09  日本学術振興会 特別研究員（DC1）
• 2009/04 - 2011/03  Kyoto Institute of TechnologyGraduate School of Science and Technology
• 2006/04 - 2009/03  Kyoto Institute of TechnologyUndergraduate Program of Applied Biology, School of Science and Technology
• Kyoto University of Education

Association Memberships

• THE JAPANESE SOCIETY FOR NEUROCHEMISTRY   日本神経内分泌学会   日本解剖学会   日本神経科学学会   

Published Papers

• Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25–Nrf2 pathway

  Tatsuhide Tanaka; Hiroaki Okuda; Ayami Isonishi; Yuki Terada; Masahiro Kitabatake; Takeaki Shinjo; Kazuya Nishimura; Shoko Takemura; Hidemasa Furue; Toshihiro Ito; Kouko Tatsumi; Akio Wanaka

  Nature Immunology Springer Science and Business Media LLC 24 (3) 439 - 451 1529-2908 2023/01 [Refereed]
  
• Juvenile social isolation affects the structure of the tanycyte–vascular interface in the hypophyseal portal system of the adult mice

  Shoko Takemura; Ayami Isonishi; Noriko Horii-Hayashi; Tatsuhide Tanaka; Kouko Tatsumi; Takashi Komori; Kazuhiko Yamamuro; Mariko Yamano; Mayumi Nishi; Manabu Makinodan; Akio Wanaka

  Neurochemistry International Elsevier BV 105439 - 105439 0197-0186 2022/11
• Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain

  Kouko Tatsumi; Kaoru Kinugawa; Ayami Isonishi; Masahiro Kitabatake; Hiroaki Okuda; Shoko Takemura; Tatsuhide Tanaka; Eiichiro Mori; Akio Wanaka

  Molecular Brain Springer Science and Business Media LLC 14 (1) 2021/12
• Large‐scale electron microscopic volume imaging of interfascicular oligodendrocytes in the mouse corpus callosum

  Tatsuhide Tanaka; Nobuhiko Ohno; Yasuyuki Osanai; Sei Saitoh; Truc Quynh Thai; Kazuya Nishimura; Takeaki Shinjo; Shoko Takemura; Kouko Tatsumi; Akio Wanaka

  Glia Wiley 0894-1491 2021/06
• SNX25 regulates proinflammatory cytokine expression via the NF-κB signal in macrophages.

  Kazuya Nishimura; Tatsuhide Tanaka; Shoko Takemura; Kouko Tatsumi; Akio Wanaka

  PloS one 16 (3) e0247840  2021
• Neural expression of sorting nexin 25 and its regulation of tyrosine receptor kinase B trafficking.

  Shoko Takemura; Ayami Isonishi; Tatsuhide Tanaka; Hiroaki Okuda; Kouko Tatsumi; Mariko Yamano; Akio Wanaka

  Brain structure & function 225 (9) 2615 - 2642 2020/12 [Refereed]
  
• Depletion of microglia and macrophages with clodronate liposomes attenuates zymosan-induced Fos expression and hypothermia in the adult mouse.

  Shohei Takagi; Saki Murayama; Katsuhiro Torii; Shoko Takemura-Morita; Erkin Kurganov; Sumiharu Nagaoka; Akio Wanaka; Seiji Miyata

  Journal of neuroimmunology 344 577244 - 577244 2020/07 [Refereed]
  
• Circadian rhythms of sorting nexin 25 in the mouse suprachiasmatic nucleus.

  Shoko Takemura; Mamoru Nagano; Ayami Isonishi; Tatsuhide Tanaka; Kouko Tatsumi; Mariko Yamano; Yoichi Minami; Yasufumi Shigeyoshi; Akio Wanaka

  Neuroscience letters 727 134897 - 134897 2020/05 [Refereed]
  
• Blood-to-brain communication in the hypothalamus for energy intake regulation.

  Morita-Takemura S; Wanaka A

  Neurochemistry international 128 135 - 142 0197-0186 2019/09 [Refereed]
  
• The Role of the Wnt Signaling Pathway in Upper Jaw Development of Chick Embryo.

  Shimomura T; Kawakami M; Tatsumi K; Tanaka T; Morita-Takemura S; Kirita T; Wanaka A

  Acta histochemica et cytochemica 52 (1) 19 - 26 0044-5991 2019/02 [Refereed]
  
• Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance.

  Morita-Takemura S; Nakahara K; Hasegawa-Ishii S; Isonishi A; Tatsumi K; Okuda H; Tanaka T; Kitabatake M; Ito T; Wanaka A

  Journal of neuroinflammation Springer Science and Business Media LLC 16 (1) 39  2019/02 [Refereed]
  
• Abrogated Caveolin-1 expression via histone modification enzyme Setdb2 regulates brain edema in a mouse model of influenza-associated encephalopathy.

  Imakita N; Kitabatake M; Ouji-Sageshima N; Hara A; Morita-Takemura S; Kasahara K; Matsukawa A; Wanaka A; Mikasa K; Ito T

  Scientific reports 9 (1) 284 - 284 2019/01 [Refereed]
  
• NGF and BDNF expression in mouse DRG after spared nerve injury.

  Terada Y; Morita-Takemura S; Isonishi A; Tanaka T; Okuda H; Tatsumi K; Shinjo T; Kawaguchi M; Wanaka A

  Neuroscience letters Elsevier BV 686 67 - 73 0304-3940 2018/11 [Refereed]
  
• The inner mitochondrial membrane protein ANT1 modulates IL-6 expression via the JNK pathway in macrophages.

  Nakahara K; Tanaka T; Okuda H; Isonishi A; Morita-Takemura S; Tatsumi K; Wanaka A

  FEBS letters 592 (22) 3750 - 3758 0014-5793 2018/11 [Refereed]
  
• Propofol induces nuclear localization of Nrf2 under conditions of oxidative stress in cardiac H9c2 cells

  Takeaki Shinjo; Tatsuhide Tanaka; Hiroaki Okuda; Akira T. Kawaguchi; Kentaro Oh-hashi; Yuki Terada; Ayami Isonishi; Shoko Morita-Takemura; Kouko Tatsumi; Masahiko Kawaguchi; Akio Wanaka

  PLoS ONE Public Library of Science 13 (4) e0196191  1932-6203 2018/04 [Refereed]
  
• Olig2-Lineage astrocytes: A distinct subtype of astrocytes that differs from GFAP astrocytes

  Kouko Tatsumi; Ayami Isonishi; Miwako Yamasaki; Yoshie Kawabe; Shoko Morita-Takemura; Kazuki Nakahara; Yuki Terada; Takeaki Shinjo; Hiroaki Okuda; Tatsuhide Tanaka; Akio Wanaka

  Frontiers in Neuroanatomy Frontiers Media S.A. 12 (8) 8  1662-5129 2018/02 [Refereed]
  
• Microglia support ATF3-positive neurons following hypoglossal nerve axotomy

  Tatsuhide Tanaka; Koichi Murakami; Yoshio Bando; Taichi Nomura; Ayami Isonishi; Shoko Morita-Takemura; Kouko Tatsumi; Akio Wanaka; Shigetaka Yoshida

  NEUROCHEMISTRY INTERNATIONAL PERGAMON-ELSEVIER SCIENCE LTD 108 332 - 342 0197-0186 2017/09 [Refereed]
  
• Structural Reconstruction of the Perivascular Space in the Adult Mouse Neurohypophysis During an Osmotic Stimulation.

  Nishikawa K; Furube E; Morita S; Horii-Hayashi N; Nishi M; Miyata S

  Journal of Neuroendocrinology 29 (2) 2017/02 [Refereed]
  
• Changes in endothelial cell proliferation and vascular permeability after systemic lipopolysaccharide administration in the subfornical organ

  Shoko Morita-Takemura; Kazuki Nakahara; Kouko Tatsumi; Hiroaki Okuda; Tatsuhide Tanaka; Ayami Isonishi; Akio Wanaka

  JOURNAL OF NEUROIMMUNOLOGY ELSEVIER SCIENCE BV 298 132 - 137 0165-5728 2016/09 [Refereed]
  
• Voluntary Exercise Induces Astrocytic Structural Plasticity in the Globus Pallidus

  Kouko Tatsumi; Hiroaki Okuda; Shoko Morita-Takemura; Tatsuhide Tanaka; Ayami Isonishi; Takeaki Shinjo; Yuki Terada; Akio Wanaka

  FRONTIERS IN CELLULAR NEUROSCIENCE FRONTIERS MEDIA SA 10 (Jun) 165  1662-5102 2016/06 [Refereed]
  
• Hedgehog Signaling Modulates the Release of Gliotransmitters from Cultured Cerebellar Astrocytes

  Hiroaki Okuda; Kouko Tatsumi; Shoko Morita-Takemura; Kazuki Nakahara; Katsunori Nochioka; Takeaki Shinjo; Yuki Terada; Akio Wanaka

  NEUROCHEMICAL RESEARCH SPRINGER/PLENUM PUBLISHERS 41 (1-2) 278 - 289 0364-3190 2016/02 [Refereed]
  
• Heterogeneous vascular permeability and alternative diffusion barrier in sensory circumventricular organs of adult mouse brain

  Shoko Morita; Eriko Furube; Tetsuya Mannari; Hiroaki Okuda; Kouko Tatsumi; Akio Wanaka; Seiji Miyata

  CELL AND TISSUE RESEARCH SPRINGER 363 (2) 497 - 511 0302-766X 2016/02 [Refereed]
  
• Hedgehog Signaling Components Are Expressed in Choroidal Neovascularization in Laser-induced Retinal Lesion

  Katsunori Nochioka; Hiroaki Okuda; Kouko Tatsumi; Shoko Morita; Nahoko Ogata; Akio Wanaka

  ACTA HISTOCHEMICA ET CYTOCHEMICA JAPAN SOC HISTOCHEMISTRY & CYTOCHEMISTRY 49 (2) 67 - 74 0044-5991 2016 [Refereed]
  
• Vascular endothelial growth factor-dependent angiogenesis and dynamic vascular plasticity in the sensory circumventricular organs of adult mouse brain

  Shoko Morita; Eriko Furube; Tetsuya Mannari; Hiroaki Okuda; Kouko Tatsumi; Akio Wanaka; Seiji Miyata

  CELL AND TISSUE RESEARCH SPRINGER 359 (3) 865 - 884 0302-766X 2015/03 [Refereed]
  
• Retinoic acid regulates Lhx8 expression via FGF-8b to the upper jaw development of chick embryo

  Tadahiro Shimomura; Masayoshi Kawakami; Hiroaki Okuda; Kouko Tatsumi; Shoko Morita; Katsunori Nochioka; Tadaaki Kirita; Akio Wanaka

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING SOC BIOSCIENCE BIOENGINEERING JAPAN 119 (3) 260 - 266 1389-1723 2015/03 [Refereed]
  
• Astrocytic TLR4 expression and LPS-induced nuclear translocation of STAT3 in the sensory circumventricular organs of adult mouse brain

  Yousuke Nakano; Eriko Furube; Shoko Morita; Akio Wanaka; Toshihiro Nakashima; Seiji Miyata

  JOURNAL OF NEUROIMMUNOLOGY ELSEVIER SCIENCE BV 278 144 - 158 0165-5728 2015/01 [Refereed]
  
• OASIS regulates chondroitin 6-O-sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex

  Hiroaki Okuda; Kouko Tatsumi; Noriko Horii-Hayashi; Shoko Morita; Aya Okuda-Yamamoto; Kazunori Imaizumi; Akio Wanaka

  JOURNAL OF NEUROCHEMISTRY WILEY-BLACKWELL 130 (5) 612 - 625 0022-3042 2014/09 [Refereed]
  
• VEGF-dependent and PDGF-dependent dynamic neurovascular reconstruction in the neurohypophysis of adult mice

  Eriko Furube; Tetsuya Mannari; Shoko Morita; Kazunori Nishikawa; Ayaka Yoshida; Masanobu Itoh; Seiji Miyata

  JOURNAL OF ENDOCRINOLOGY BIOSCIENTIFICA LTD 222 (1) 161 - 179 0022-0795 2014/07 [Refereed]
  
• Chondroitin Sulfate Proteoglycan Tenascin-R Regulates Glutamate Uptake by Adult Brain Astrocytes

  Hiroaki Okuda; Kouko Tatsumi; Shoko Morita; Yukinao Shibukawa; Hiroaki Korekane; Noriko Horii-Hayashi; Yoshinao Wada; Naoyuki Taniguchi; Akio Wanaka

  JOURNAL OF BIOLOGICAL CHEMISTRY AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 289 (5) 2620 - 2631 0021-9258 2014/01 [Refereed]
  
• Geissoschizine Methyl Ether, an Alkaloid from the Uncaria Hook, Improves Remyelination After Cuprizone-Induced Demyelination in Medial Prefrontal Cortex of Adult Mice

  Shoko Morita; Kouko Tatsumi; Manabu Makinodan; Hiroaki Okuda; Toshifumi Kishimoto; Akio Wanaka

  NEUROCHEMICAL RESEARCH SPRINGER/PLENUM PUBLISHERS 39 (1) 59 - 67 0364-3190 2014/01 [Refereed]
  
• Changes in pericytic expression of NG2 and PDGFRB and vascular permeability in the sensory circumventricular organs of adult mouse by osmotic stimulation

  Shoko Morita; Atsushi Hourai; Seiji Miyata

  CELL BIOCHEMISTRY AND FUNCTION WILEY-BLACKWELL 32 (1) 51 - 61 0263-6484 2014/01 [Refereed]
  
• Accessibility of low-molecular-mass molecules to the median eminence and arcuate hypothalamic nucleus of adult mouse

  Shoko Morita; Seiji Miyata

  CELL BIOCHEMISTRY AND FUNCTION WILEY-BLACKWELL 31 (8) 668 - 677 0263-6484 2013/12 [Refereed]
  
• Synaptic localization of growth-associated protein 43 in cultured hippocampal neurons during synaptogenesis

  Shoko Morita; Seiji Miyata

  CELL BIOCHEMISTRY AND FUNCTION WILEY-BLACKWELL 31 (5) 400 - 411 0263-6484 2013/07 [Refereed]
  
• Astrocytic TRPV1 ion channels detect blood-borne signals in the sensory circumventricular organs of adult mouse brains

  Tetsuya Mannari; Shoko Morita; Eriko Furube; Makoto Tominaga; Seiji Miyata

  GLIA WILEY-BLACKWELL 61 (6) 957 - 971 0894-1491 2013/06 [Refereed]
  
• VEGF-dependent continuous angiogenesis in the median eminence of adult mice

  S. Morita; S. Ukai; S. Miyata

  EUROPEAN JOURNAL OF NEUROSCIENCE WILEY-BLACKWELL 37 (4) 508 - 518 0953-816X 2013/02 [Refereed]
  
• Different vascular permeability between the sensory and secretory circumventricular organs of adult mouse brain

  Shoko Morita; Seiji Miyata

  CELL AND TISSUE RESEARCH SPRINGER 349 (2) 589 - 603 0302-766X 2012/08 [Refereed]
  
• Overexpression of IgLON cell adhesion molecules changes proliferation and cell size of cortical astrocytes

  Chiaki Sugimoto; Shoko Morita; Seiji Miyata

  CELL BIOCHEMISTRY AND FUNCTION WILEY-BLACKWELL 30 (5) 400 - 405 0263-6484 2012/07 [Refereed]
  
• Effect of pleiotrophin on glutamate-induced neurotoxicity in cultured hippocampal neurons

  Hitomi Asai; Shoko Morita; Seiji Miyata

  CELL BIOCHEMISTRY AND FUNCTION WILEY-BLACKWELL 29 (8) 660 - 665 0263-6484 2011/12 [Refereed]
  
• A new method for visualization of endothelial cells and extravascular leakage in adult mouse brain using fluorescein isothiocyanate

  Seiji Miyata; Shoko Morita

  JOURNAL OF NEUROSCIENCE METHODS ELSEVIER SCIENCE BV 202 (1) 9 - 16 0165-0270 2011/10 [Refereed]
  
• Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus

  Yuki Taniguchi; Naoko Inoue; Shoko Morita; Yoshikazu Nikaido; Toshihiro Nakashima; Nobuo Nagai; Kiyotaka Okada; Osamu Matsuo; Seiji Miyata

  CELL AND TISSUE RESEARCH SPRINGER 343 (2) 303 - 317 0302-766X 2011/02 [Refereed]
  
• Tissue Plasminogen Activator and Plasminogen Are Critical for Osmotic Homeostasis by Regulating Vasopressin Secretion

  Yuhki Imamura; Shoko Morita; Yoshihiro Nakatani; Kiyotaka Okada; Shigeru Ueshima; Osamu Matsuo; Seiji Miyata

  JOURNAL OF NEUROSCIENCE RESEARCH WILEY-LISS 88 (9) 1995 - 2006 0360-4012 2010/07 [Refereed]
  
• ACTIVITY-DEPENDENT REMODELING OF CHONDROITIN SULFATE PROTEOGLYCANS EXTRACELLULAR MATRIX IN THE HYPOTHALAMO-NEUROHYPOPHYSIAL SYSTEM

  S. Morita; A. Oohira; S. Miyata

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 166 (4) 1068 - 1082 0306-4522 2010/04 [Refereed]
  
• FUNCTIONAL DIFFERENCE OF RECEPTOR-TYPE PROTEIN TYROSINE PHOSPHATASE zeta/beta ISOFORMS IN NEUROGENESIS OF HIPPOCAMPAL NEURONS

  H. Asai; S. Yokoyama; S. Morita; N. Maeda; S. Miyata

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 164 (3) 1020 - 1030 0306-4522 2009/12 [Refereed]
  
• Expression of chondroitin sulfate proteoglycans in barrel field of mouse and rat somatosensory cortex

  Michiru Nakamura; Keiko Nakano; Shoko Morita; Toshihiro Nakashima; Atsuhiko Oohira; Seiji Miyata

  BRAIN RESEARCH ELSEVIER SCIENCE BV 1252 117 - 129 0006-8993 2009/02 [Refereed]
  

Books etc

• 精神医学領域の論文を読みこなすキーワード100！

  (86. 血液脳関門)9784880028866

MISC

• 幼少期の隔離飼育は成体マウス視床下部正中隆起のタニサイト 血管境界域の構造に影響を与える

  竹村 晶子; 石西 綾美; 堀井 謹子[林]; 田中 達英; 辰巳 晃子; 小森 崇史; 山室 和彦; 西 真弓; 牧之段 学; 和中 明生  日本内分泌学会雑誌  97-  (5)  1250  -1250  2022/03
• 「脳の窓」脳室周囲器官の動的な血管構築から読み解く脳と全身の情報交換機構

  竹村 晶子[森田]  神経化学  59-  (2)  52  -58  2020/12
• 痛覚鈍麻マウスの順遺伝学スクリーニングによる新規疼痛候補遺伝子の同定

  田中達英; 奥田洋明; 寺田雄紀; 新城武明; 西村和也; 石西綾美; 竹村晶子; 辰巳晃子; 和中明生  日本解剖学会総会・全国学術集会講演プログラム・抄録集  125th-  2020
• 中枢神経系におけるsorting nexin25の発現分布と脳由来神経栄養因子受容体の発現調節における役割

  竹村晶子; 石西綾美; 田中達英; 奥田洋明; 辰巳晃子; 和中明生  日本解剖学会総会・全国学術集会講演プログラム・抄録集  125th-  2020
• ANT1の発現を低下させると炎症が抑制される

  中原 一貴; 達英; 奥田 洋明; 石西 綾美; 森田 晶子; 村; 辰巳 晃子; 和中 明生  生命科学系学会合同年次大会  2017年度-  [2P  -0266]  2017/12
• Astrocytic chondroitin sulfate proteoglycans in brain injury and in glutamate uptake function

  A. Wanaka; H. Okuda; K. Tatsumi; S. Morita; K. Nakahara  JOURNAL OF NEUROCHEMISTRY  134-  108  -109  2015/08
• 抑肝散研究の基礎と臨床最前線 統合失調症モデルマウスに対する抑肝散及びその生薬成分の効果

  和中 明生; 辰巳 晃子; 森田 晶子; 奥田 洋明; 牧之段 学; 岸本 年史  日本脳科学会プログラム・抄録集  41回-  19  -19  2014/11
• VEGFとPDGFに依存した下垂体後葉の血管新生と終末-血管のダイナミクス

  古部 瑛莉子; 萬成 哲也; 森田 晶子; 宮田 清司  日本内分泌学会雑誌  90-  (2)  607  -607  2014/09
• 脳弓下器官の血管リモデリング 炎症反応における役割

  森田 晶子; 中原 一貴; 辰巳 晃子; 奥田 洋明; 蓬莱 敦; 宮田 清司; 和中 明生  日本内分泌学会雑誌  90-  (2)  602  -602  2014/09
• Active participation of vasculature in immune-to-brain communication in the sensory circumventricular organs

  S. Morita; K. Nakahara; E. Furube; K. Tatsumi; H. Okuda; A. Hourai; S. Miyata; A. Wanaka  JOURNAL OF NEUROCHEMISTRY  130-  49  -49  2014/08
• Astrocytes in the adult globus pallidus change morphologies in response to motor activities

  K. Tatsumi; H. Okuda; S. Morita; A. Wanaka  JOURNAL OF NEUROCHEMISTRY  130-  49  -49  2014/08
• 浸透圧刺激による脳室周囲器官の血管構築変化

  森田 晶子; 蓬莱 敦; 鵜飼 真璃; 奥田 洋明; 辰巳 晃子; 和中 明生; 宮田 清司  解剖学雑誌  87-  (2)  36  -36  2012/06
• Microenvironment for neurogenesis and angiogenesis in the circumventricular organs

  Shinri Ukai; Natsuki Iimori; Shoko Morita; Seiji Miyata  NEUROSCIENCE RESEARCH  71-  E224  -E224  2011
• The mechanism of vascular reconstruction in the adult circumventricular organs

  Shoko Morita; Tetsuya Mannari; Seiji Miyata  NEUROSCIENCE RESEARCH  71-  E224  -E224  2011
• Effects of blood-derived parameters on vascular reconstruction in the circumventricular organs

  Atsushi Hourai; Shoko Morita; Seiji Miyata  NEUROSCIENCE RESEARCH  71-  E224  -E224  2011
• Localization of tissue plasminogen activator and plasminogen in the mouse hypothalamus

  Yuki Taniguchi; Shoko Morita; Naoko Inoue; Seiji Miyata  NEUROSCIENCE RESEARCH  68-  E355  -E355  2010
• Neurogliogenesis and angiogenesis in adult circumventricular organs

  Shoko Morita; Shinri Ukai; Seiji Miyata  NEUROSCIENCE RESEARCH  68-  E357  -E358  2010
• Vesicular localization of tPA and plasminogen in barin neurons

  Seiji Miyata; Naoko Inoue; Shoko Morita; Atsushi Hourai  NEUROSCIENCE RESEARCH  68-  E355  -E356  2010
• Activity-dependent changes in expression of chondroitin sulfate proteoglycan

  Shoko Morita; Atsuhiko Oohira; Seiji Miyata  NEUROSCIENCE RESEARCH  65-  S98  -S98  2009

Awards & Honors

• 2020/09 日本神経化学会 The Award for Young Investigator of Japanese Society for Neurochemistry
   

  受賞者: 竹村晶子
• 2019/12 国際ソロプチミスト奈良クラブ賞女性研究者賞
   

  受賞者: 竹村 晶子
• 2011/11 日本神経内分泌学会若手研究奨励賞
   

  受賞者: 森田 晶子

Research Grants & Projects

• 高脂肪食摂取による肥満と脳の炎症～マクロファージに着目して～

  文部科学省：科学研究費補助金（基盤研究（C））

  Date (from‐to) : 2019/04 -2022/03 

  Author : 竹村晶子
• A new subpopulation of astrocytes that subserve GABAergic neural transmission in the brain.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2018/04 -2021/03 

  Author : Wanaka Akio

   

  We found Olig2-expressing astrocytes, which are distinct from GFAP-expressing astrocytes. Olig2-astrocytes are distributed widely in the adult brain. They are localized to the brain nuclei known to contain inhibitory neuronal terminals, suggesting that Olig2-astrocytes may be involved in the inhibitory GABAergic transmission as a component of "tripartite synapse". The globus pallidus (GPe) is one of the representative nucleus that contains a number of Olig2-astrocytes. Interestingly, Olig2-astrocytes and GFAP-astrocytes occupied mutually-exclusive teritories in the GPe. We found that the processes of Olig2-astrocytes were associated with GABAergic neuronal terminals. We tried to knock-down GAT-3, a glial GABA transporter, with adeno-associated virus vector harboring shRNA of GAT-3. The knock-down efficiency was unfortunately low and we did not see any effects on behaviors of virus vector-transduced mice.
• 高脂肪食がもたらす脳の炎症と肥満の関係ー脳に侵入するマクロファージに着目してー

  公益財団法人 三島海雲記念財団：2019年度学術研究奨励金申請書【自然科学部門】

  Date (from‐to) : 2019/06 -2020/05 

  Author : 竹村晶子
• 脳室周囲器官は炎症情報を脳実質に伝える窓口である－血管周囲免疫細胞の役割－

  文部科学省：科学研究費補助金（若手研究（B））

  Date (from‐to) : 2016/04 -2019/03 

  Author : 森田 晶子
• 免疫応答における「脳の窓」感知系脳室周囲器官の物質透過制限機構

  東京工業大学基金：平成26年度研究助成

  Date (from‐to) : 2014/04 -2015/03 

  Author : 森田 晶子
• Cellular mechanisms of vascular remodeling for homeostasis in the sensory circumventricular organs

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2014 -2015 

  Author : Morita Shoko

   

  The sensory circumventricular organs (CVOs), which comprise the organum vasculosum of the lamina terminalis, the subfornical organ and the area postrema, lack a typical blood-brain barrier and monitor directly blood-derived information to regulate body fluid homeostasis, inflammation, feeding, nausea and vomiting. Until now, almost nothing has been documented about vascular features of the sensory CVOs except fenestration of vascular endothelial cells. I demonstrated that continuous angiogenesis occurs in the adult sensory CVOs. My data indicate that continuous angiogenesis is dependent on vascular endothelial growth factor signaling and responsible for the dynamic plasticity of vascular structure and permeability.
• 感知系脳室周囲器官における血管新生の生理的意義の解明とその人為的制御

  奈良県立医科大学：奈良県立医科大学第一回若手研究者助成事業

  Date (from‐to) : 2013/04 -2014/03 

  Author : 森田 晶子
• 脳におけるコンドロイチン硫酸プロテオグリカンと神経回路可塑性

  文部科科学省：科学研究費補助金（特別研究員奨励費）

  Date (from‐to) : 2011/04 -2012/09 

  Author : 森田 晶子

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https://researchmap.jp/morit